The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study
Recent evidence suggests an association between hypertension and periodontitis, although the pathways and implications underlying both chronic conditions are still poorly understood. Therefore, the aim of this study was to evaluate the relationship between hypertension and periodontitis through an o...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/15/5140 |
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| author | Rossana Abud Cabrera Rosa João Victor Soares Rodrigues Marina Module Cláudio João Paulo Soares Franciscon Gabriel Mulinari-Santos Thamiris Cirelli Rafael Scaf de Molon Valdir Gouveia Garcia Leticia Helena Theodoro |
| author_facet | Rossana Abud Cabrera Rosa João Victor Soares Rodrigues Marina Module Cláudio João Paulo Soares Franciscon Gabriel Mulinari-Santos Thamiris Cirelli Rafael Scaf de Molon Valdir Gouveia Garcia Leticia Helena Theodoro |
| author_sort | Rossana Abud Cabrera Rosa |
| collection | DOAJ |
| description | Recent evidence suggests an association between hypertension and periodontitis, although the pathways and implications underlying both chronic conditions are still poorly understood. Therefore, the aim of this study was to evaluate the relationship between hypertension and periodontitis through an observational clinical study using periodontal, physical, and biochemical analyses in hypertensive and non-hypertensive individuals with periodontitis. A total of one hundred patients were divided into two groups. The first group was hypertensive patients with periodontitis. The second group was non-hypertensive patients with periodontitis. Periodontal parameters of probing depth, bleeding on probing, and clinical attachment level were evaluated. The systolic, diastolic, mean, and differential blood pressure were measured in the physical examination. In addition, body mass index and waist–hip ratio were verified. Biochemical tests for glycated hemoglobin, fasting blood glucose, estimated blood glucose, total cholesterol, high-density lipoprotein, creatinine, glutamate pyruvate transaminase, glutamic oxaloacetic transaminase, and C-reactive protein were evaluated. The data were submitted for statistical analysis (α = 0.05%). The results of this study demonstrated that patients with cardiovascular disease did not present with worse periodontal clinical parameters in the conditions studied. However, it is important to bear in mind that this cross-sectional study has some inherent limitations to its design; therefore, to study the relationship between hypertension and periodontitis further, an interventional randomized clinical trial should be conducted. |
| first_indexed | 2024-03-11T00:23:11Z |
| format | Article |
| id | doaj.art-28d88f0f0f36413bbe14bb2bd40f5816 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T00:23:11Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-28d88f0f0f36413bbe14bb2bd40f58162023-11-18T23:09:54ZengMDPI AGJournal of Clinical Medicine2077-03832023-08-011215514010.3390/jcm12155140The Relationship between Hypertension and Periodontitis: A Cross-Sectional StudyRossana Abud Cabrera Rosa0João Victor Soares Rodrigues1Marina Module Cláudio2João Paulo Soares Franciscon3Gabriel Mulinari-Santos4Thamiris Cirelli5Rafael Scaf de Molon6Valdir Gouveia Garcia7Leticia Helena Theodoro8Department of Diagnostic and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, BrazilDepartment of Diagnostic and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, BrazilDepartment of Diagnostic and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, BrazilDepartment of Diagnostic and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, BrazilDepartment of Diagnostic and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, BrazilDepartment of Dentistry, University Center of Associated School (UNIFAE), São João da Boa Vista 13870-377, SP, BrazilDepartment of Diagnostic and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, BrazilLatin American Institute of Dental Research and Education (ILAPEO), Curitiba 80710-150, PR, BrazilDepartment of Diagnostic and Surgery, School of Dentistry, São Paulo State University (UNESP), Araçatuba 16015-050, SP, BrazilRecent evidence suggests an association between hypertension and periodontitis, although the pathways and implications underlying both chronic conditions are still poorly understood. Therefore, the aim of this study was to evaluate the relationship between hypertension and periodontitis through an observational clinical study using periodontal, physical, and biochemical analyses in hypertensive and non-hypertensive individuals with periodontitis. A total of one hundred patients were divided into two groups. The first group was hypertensive patients with periodontitis. The second group was non-hypertensive patients with periodontitis. Periodontal parameters of probing depth, bleeding on probing, and clinical attachment level were evaluated. The systolic, diastolic, mean, and differential blood pressure were measured in the physical examination. In addition, body mass index and waist–hip ratio were verified. Biochemical tests for glycated hemoglobin, fasting blood glucose, estimated blood glucose, total cholesterol, high-density lipoprotein, creatinine, glutamate pyruvate transaminase, glutamic oxaloacetic transaminase, and C-reactive protein were evaluated. The data were submitted for statistical analysis (α = 0.05%). The results of this study demonstrated that patients with cardiovascular disease did not present with worse periodontal clinical parameters in the conditions studied. However, it is important to bear in mind that this cross-sectional study has some inherent limitations to its design; therefore, to study the relationship between hypertension and periodontitis further, an interventional randomized clinical trial should be conducted.https://www.mdpi.com/2077-0383/12/15/5140periodontitishypertensioninflammationobservational study |
| spellingShingle | Rossana Abud Cabrera Rosa João Victor Soares Rodrigues Marina Module Cláudio João Paulo Soares Franciscon Gabriel Mulinari-Santos Thamiris Cirelli Rafael Scaf de Molon Valdir Gouveia Garcia Leticia Helena Theodoro The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study Journal of Clinical Medicine periodontitis hypertension inflammation observational study |
| title | The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study |
| title_full | The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study |
| title_fullStr | The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study |
| title_full_unstemmed | The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study |
| title_short | The Relationship between Hypertension and Periodontitis: A Cross-Sectional Study |
| title_sort | relationship between hypertension and periodontitis a cross sectional study |
| topic | periodontitis hypertension inflammation observational study |
| url | https://www.mdpi.com/2077-0383/12/15/5140 |
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