Discovery of Novel Human Gene Regulatory Modules from Gene Co-expression and Promoter Motif Analysis
Abstract Deciphering gene regulatory networks requires identification of gene expression modules. We describe a novel bottom-up approach to identify gene modules regulated by cis-regulatory motifs from a human gene co-expression network. Target genes of a cis-regulatory motif were identified from th...
Main Authors: | Shisong Ma, Michael Snyder, Savithramma P. Dinesh-Kumar |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-05705-2 |
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