Modelling the contribution of the hypnozoite reservoir to Plasmodium vivax transmission

Modelling the contribution of the hypnozoite reservoir to Plasmodium vivax transmission

Plasmodium vivax relapse infections occur following activation of latent liver-stages parasites (hypnozoites) causing new blood-stage infections weeks to months after the initial infection. We develop a within-host mathematical model of liver-stage hypnozoites, and validate it against data from trop...

Full description

Bibliographic Details
Main Authors: Michael T White, Stephan Karl, Katherine E Battle, Simon I Hay, Ivo Mueller, Azra C Ghani
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-11-01
Series:eLife
Subjects:
malaria
vivax
relapse
mathematical
model
Online Access:https://elifesciences.org/articles/04692

Similar Items

Similar Items