Q94 is not a selective modulator of proteinase-activated receptor 1 (PAR1) in platelets

Thrombin is a potent platelet activator, acting through proteinase-activated receptors −1 and −4 (PAR1 and PAR4). Of these, PAR-1 is activated more rapidly and by lower thrombin concentrations. Consequently, PAR-1 has been extensively investigated as a target for anti-platelet drugs to prevent myoca...

Повний опис

Бібліографічні деталі
Автори: Luc R. A. Francis, Sarah L. Millington-Burgess, Taufiq Rahman, Matthew T. Harper
Формат: Стаття
Мова:English
Опубліковано: Taylor & Francis Group 2022-10-01
Серія:Platelets
Предмети:
Онлайн доступ:http://dx.doi.org/10.1080/09537104.2022.2026911