Involvement of abnormal dystroglycan expression and matriglycan levels in cancer pathogenesis

Abstract Dystroglycan (DG) is a glycoprotein composed of two subunits that remain non-covalently bound at the plasma membrane: α-DG, which is extracellular and heavily O-mannosyl glycosylated, and β-DG, an integral transmembrane polypeptide. α-DG is involved in the maintenance of tissue integrity an...

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Bibliographic Details
Main Authors: Cristina Quereda, Àngels Pastor, José Martín-Nieto
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-022-02812-7