Gene expression changes in sickle cell reticulocytes and their clinical associations

Gene expression changes in sickle cell reticulocytes and their clinical associations

Abstract Transcriptional changes in compensatory erythropoiesis in sickle cell anemia (SCA) and their disease modulation are unclear. We detected 1226 differentially expressed genes in hemoglobin SS reticulocytes compared to non-anemic hemoglobin AA controls. Assessing developmental expression chang...

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Podrobná bibliografie
Hlavní autoři: Xu Zhang, Jihyun Song, Binal N. Shah, Jin Han, Taif Hassan, Galina Miasniakova, Adelina Sergueeva, Sergei Nekhai, Roberto F. Machado, Mark T. Gladwin, Santosh L. Saraf, Josef T. Prchal, Victor R. Gordeuk
Médium: Článek
Jazyk:English
Vydáno: Nature Portfolio 2023-08-01
Edice:Scientific Reports
On-line přístup:https://doi.org/10.1038/s41598-023-40039-2

Internet

https://doi.org/10.1038/s41598-023-40039-2

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