Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2
Transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurs through respiratory droplets passed directly from person to person or indirectly through fomites, such as common use surfaces or objects. The aim of this study was to determine the virucidal efficacy of blue LED...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/13/8/1436 |
| _version_ | 1797521845886386176 |
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| author | Amanda Gardner Sayani Ghosh Magdalena Dunowska Gale Brightwell |
| author_facet | Amanda Gardner Sayani Ghosh Magdalena Dunowska Gale Brightwell |
| author_sort | Amanda Gardner |
| collection | DOAJ |
| description | Transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurs through respiratory droplets passed directly from person to person or indirectly through fomites, such as common use surfaces or objects. The aim of this study was to determine the virucidal efficacy of blue LED (405 nm) and far-UVC (222 nm) light in comparison to standard UVC (254 nm) irradiation for the inactivation of feline infectious peritonitis virus (FIPV) on different matrices as a model for SARS-CoV-2. Wet or dried FIPV on stainless steel, plastic, or paper discs, in the presence or absence of artificial saliva, were exposed to various wavelengths of light for different time periods (1–90 min). Dual activity of blue LED and far-UVC lights were virucidal for most wet and dried FIPV within 4 to 16 min on all matrices. Individual action of blue LED and far-UVC lights were virucidal for wet FIPV but required longer irradiation times (8–90 min) to reach a 4-log reduction. In comparison, LED (265 nm) and germicidal UVC (254 nm) were virucidal on almost all matrices for both wet and dried FIPV within 1 min exposure. UVC was more effective for the disinfection of surfaces as compared to blue LED and far-UVC individually or together. However, dual action of blue LED and far-UVC was virucidal. This combination of lights could be used as a safer alternative to traditional UVC. |
| first_indexed | 2024-03-10T08:18:19Z |
| format | Article |
| id | doaj.art-28e348cded574c2c988c9bcf6f89c134 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T08:18:19Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-28e348cded574c2c988c9bcf6f89c1342023-11-22T10:09:12ZengMDPI AGViruses1999-49152021-07-01138143610.3390/v13081436Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2Amanda Gardner0Sayani Ghosh1Magdalena Dunowska2Gale Brightwell3AgResearch Ltd., Hopkirk Research Institute, Massey University, Corner University Ave and Library Road, Palmerston North 4442, New ZealandSchool of Veterinary Science, Massey University Manawatu (Turitea), Tennent Drive, Palmerston North 4474, New ZealandSchool of Veterinary Science, Massey University Manawatu (Turitea), Tennent Drive, Palmerston North 4474, New ZealandAgResearch Ltd., Hopkirk Research Institute, Massey University, Corner University Ave and Library Road, Palmerston North 4442, New ZealandTransmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurs through respiratory droplets passed directly from person to person or indirectly through fomites, such as common use surfaces or objects. The aim of this study was to determine the virucidal efficacy of blue LED (405 nm) and far-UVC (222 nm) light in comparison to standard UVC (254 nm) irradiation for the inactivation of feline infectious peritonitis virus (FIPV) on different matrices as a model for SARS-CoV-2. Wet or dried FIPV on stainless steel, plastic, or paper discs, in the presence or absence of artificial saliva, were exposed to various wavelengths of light for different time periods (1–90 min). Dual activity of blue LED and far-UVC lights were virucidal for most wet and dried FIPV within 4 to 16 min on all matrices. Individual action of blue LED and far-UVC lights were virucidal for wet FIPV but required longer irradiation times (8–90 min) to reach a 4-log reduction. In comparison, LED (265 nm) and germicidal UVC (254 nm) were virucidal on almost all matrices for both wet and dried FIPV within 1 min exposure. UVC was more effective for the disinfection of surfaces as compared to blue LED and far-UVC individually or together. However, dual action of blue LED and far-UVC was virucidal. This combination of lights could be used as a safer alternative to traditional UVC.https://www.mdpi.com/1999-4915/13/8/1436405 nm blue lightfar-UVCultraviolet lightfeline infectious peritonitis virusviral inactivationlight disinfection |
| spellingShingle | Amanda Gardner Sayani Ghosh Magdalena Dunowska Gale Brightwell Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2 Viruses 405 nm blue light far-UVC ultraviolet light feline infectious peritonitis virus viral inactivation light disinfection |
| title | Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2 |
| title_full | Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2 |
| title_fullStr | Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2 |
| title_full_unstemmed | Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2 |
| title_short | Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2 |
| title_sort | virucidal efficacy of blue led and far uvc light disinfection against feline infectious peritonitis virus as a model for sars cov 2 |
| topic | 405 nm blue light far-UVC ultraviolet light feline infectious peritonitis virus viral inactivation light disinfection |
| url | https://www.mdpi.com/1999-4915/13/8/1436 |
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