The impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery: A systematic review and meta-analysis.
<h4>Background</h4>Sarcopenia is defined as the loss of muscle mass combined with loss of muscle strength, with or without loss of muscle performance. The use of this parameter as a risk factor for complications after surgery is not currently used. This meta-analysis aims to assess the i...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2020-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0237740 |
| _version_ | 1818675302806585344 |
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| author | Leonardo Zumerkorn Pipek Carlos Guilherme Baptista Rafaela Farias Vidigal Nascimento João Victor Taba Milena Oliveira Suzuki Fernanda Sayuri do Nascimento Diego Ramos Martines Fernanda Nii Leandro Ryuchi Iuamoto Luiz Augusto Carneiro-D'Albuquerque Alberto Meyer Wellington Andraus |
| author_facet | Leonardo Zumerkorn Pipek Carlos Guilherme Baptista Rafaela Farias Vidigal Nascimento João Victor Taba Milena Oliveira Suzuki Fernanda Sayuri do Nascimento Diego Ramos Martines Fernanda Nii Leandro Ryuchi Iuamoto Luiz Augusto Carneiro-D'Albuquerque Alberto Meyer Wellington Andraus |
| author_sort | Leonardo Zumerkorn Pipek |
| collection | DOAJ |
| description | <h4>Background</h4>Sarcopenia is defined as the loss of muscle mass combined with loss of muscle strength, with or without loss of muscle performance. The use of this parameter as a risk factor for complications after surgery is not currently used. This meta-analysis aims to assess the impact of sarcopenia defined by radiologically and clinically criteria and its relationship with complications after gastrointestinal surgeries.<h4>Materials and methods</h4>A review of the literature was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (PROSPERO registration number: CRD42019132221). Articles were selected from the PUBMED and EMBASE databases that adequately assessed sarcopenia and its impact on postoperative complications in gastrointestinal surgery patients. Pooled estimates of pre-operative outcome data were calculated using the odds ratio (OR) and 95% confidence interval (CI). Subgroup analysis were performed to assess each type of surgery.<h4>Results</h4>The search strategy returned 1323, with 11 studies meeting the inclusion criteria. A total of 4265 patients were analysed. The prevalence of sarcopenia between studies ranged from 6.8% to 35.9%. The meta-analysis showed an OR for complications after surgery of 3.01 (95% CI 2.55-3.55) and an OR of 2.2 (95% CI 1.44-3.36) for hospital readmission (30 days).<h4>Conclusion</h4>Sarcopenia, when properly diagnosed, is associated with an increase in late postoperative complications, as well as an increase in the number of postoperative hospital readmissions for various types of gastrointestinal surgery. We believe that any preoperative evaluation should include, in a patient at risk, tests for the diagnosis of sarcopenia and appropriate procedures to reduce its impact on the patient's health. |
| first_indexed | 2024-12-17T08:25:26Z |
| format | Article |
| id | doaj.art-28e44211398c43d7a4e48faa6c771eae |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-17T08:25:26Z |
| publishDate | 2020-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-28e44211398c43d7a4e48faa6c771eae2022-12-21T21:56:48ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01158e023774010.1371/journal.pone.0237740The impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery: A systematic review and meta-analysis.Leonardo Zumerkorn PipekCarlos Guilherme BaptistaRafaela Farias Vidigal NascimentoJoão Victor TabaMilena Oliveira SuzukiFernanda Sayuri do NascimentoDiego Ramos MartinesFernanda NiiLeandro Ryuchi IuamotoLuiz Augusto Carneiro-D'AlbuquerqueAlberto MeyerWellington Andraus<h4>Background</h4>Sarcopenia is defined as the loss of muscle mass combined with loss of muscle strength, with or without loss of muscle performance. The use of this parameter as a risk factor for complications after surgery is not currently used. This meta-analysis aims to assess the impact of sarcopenia defined by radiologically and clinically criteria and its relationship with complications after gastrointestinal surgeries.<h4>Materials and methods</h4>A review of the literature was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines (PROSPERO registration number: CRD42019132221). Articles were selected from the PUBMED and EMBASE databases that adequately assessed sarcopenia and its impact on postoperative complications in gastrointestinal surgery patients. Pooled estimates of pre-operative outcome data were calculated using the odds ratio (OR) and 95% confidence interval (CI). Subgroup analysis were performed to assess each type of surgery.<h4>Results</h4>The search strategy returned 1323, with 11 studies meeting the inclusion criteria. A total of 4265 patients were analysed. The prevalence of sarcopenia between studies ranged from 6.8% to 35.9%. The meta-analysis showed an OR for complications after surgery of 3.01 (95% CI 2.55-3.55) and an OR of 2.2 (95% CI 1.44-3.36) for hospital readmission (30 days).<h4>Conclusion</h4>Sarcopenia, when properly diagnosed, is associated with an increase in late postoperative complications, as well as an increase in the number of postoperative hospital readmissions for various types of gastrointestinal surgery. We believe that any preoperative evaluation should include, in a patient at risk, tests for the diagnosis of sarcopenia and appropriate procedures to reduce its impact on the patient's health.https://doi.org/10.1371/journal.pone.0237740 |
| spellingShingle | Leonardo Zumerkorn Pipek Carlos Guilherme Baptista Rafaela Farias Vidigal Nascimento João Victor Taba Milena Oliveira Suzuki Fernanda Sayuri do Nascimento Diego Ramos Martines Fernanda Nii Leandro Ryuchi Iuamoto Luiz Augusto Carneiro-D'Albuquerque Alberto Meyer Wellington Andraus The impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery: A systematic review and meta-analysis. PLoS ONE |
| title | The impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery: A systematic review and meta-analysis. |
| title_full | The impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery: A systematic review and meta-analysis. |
| title_fullStr | The impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery: A systematic review and meta-analysis. |
| title_full_unstemmed | The impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery: A systematic review and meta-analysis. |
| title_short | The impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery: A systematic review and meta-analysis. |
| title_sort | impact of properly diagnosed sarcopenia on postoperative outcomes after gastrointestinal surgery a systematic review and meta analysis |
| url | https://doi.org/10.1371/journal.pone.0237740 |
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