Biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fracture

Background: The purpose of this study was to determine the difference in complication rates between males and females undergoing reverse shoulder arthroplasty for proximal humerus fractures. We hypothesized that (1) females were more likely to undergo reverse shoulder arthroplasty for fracture, and...

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Main Authors: Chimere O. Ezuma, BS, Rashed L. Kosber, BA, David Kovacevic, MD
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:JSES International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666638321000463
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author Chimere O. Ezuma, BS
Rashed L. Kosber, BA
David Kovacevic, MD
author_facet Chimere O. Ezuma, BS
Rashed L. Kosber, BA
David Kovacevic, MD
author_sort Chimere O. Ezuma, BS
collection DOAJ
description Background: The purpose of this study was to determine the difference in complication rates between males and females undergoing reverse shoulder arthroplasty for proximal humerus fractures. We hypothesized that (1) females were more likely to undergo reverse shoulder arthroplasty for fracture, and (2) males were more likely to sustain a perioperative complication. Methods: The National Surgical Quality Improvement Program database was queried to identify patients who underwent reverse shoulder arthroplasty for proximal humerus fracture between 2011 and 2018. Patients were stratified based on biological sex. Patient demographics, comorbidities, and 30-day perioperative complication rates were collected. Univariate analyses and multiple variable logistic regression modeling were performed. Results: About 905 patients were included in the analysis—175 (19.3%) were male and 730 (80.7%) were female. Males were more likely to sustain perioperative complications (26.3% vs. 14.1%; P < .001)—pneumonia (2.9% vs. 0.5%; P = .016), unplanned intubation (2.3% vs. 0.4%; P = .029), and unplanned reoperation (9.1% vs. 1.1%; P < .001). On multivariate analysis, males were at a 2.4-fold increase risk of developing any complication (OR = 2.38 [95% CI 1.55-3.65]; P < .001) and a 10-fold increase risk of returning to the operating room for an unplanned reoperation (OR = 10.59 [95% CI 4.23-27.49]; P < .001) compared with females. Conclusion: Females were more likely to undergo reverse shoulder arthroplasty for proximal humerus fracture, but males were at increased risk of sustaining short-term complications. This study provides useful information for clinicians to consider when counseling their patients during the perioperative period.
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spelling doaj.art-28e461a7d9c446ffab9a504427a8aa962022-12-21T18:47:25ZengElsevierJSES International2666-63832021-05-0153371376Biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fractureChimere O. Ezuma, BS0Rashed L. Kosber, BA1David Kovacevic, MD2Department of Orthopedic Surgery, Columbia University Medical Center, New York, NY, USADepartment of Orthopedic Surgery, Columbia University Medical Center, New York, NY, USACorresponding author: David Kovacevic, MD, Chief of Shoulder, Elbow, and Sports Medicine, NewYork-Presbyterian Lawrence Hospital, Head Team Physician Columbia Rugby, Head Team Physician Old Blue Rugby, Assistant Professor, Chief of Informatics, Department of Orthopedic Surgery, NewYork-Presbyterian / Columbia University Medical Center, 622 West 168th Street, PH-11, New York, NY 10032, USA.; Department of Orthopedic Surgery, Columbia University Medical Center, New York, NY, USABackground: The purpose of this study was to determine the difference in complication rates between males and females undergoing reverse shoulder arthroplasty for proximal humerus fractures. We hypothesized that (1) females were more likely to undergo reverse shoulder arthroplasty for fracture, and (2) males were more likely to sustain a perioperative complication. Methods: The National Surgical Quality Improvement Program database was queried to identify patients who underwent reverse shoulder arthroplasty for proximal humerus fracture between 2011 and 2018. Patients were stratified based on biological sex. Patient demographics, comorbidities, and 30-day perioperative complication rates were collected. Univariate analyses and multiple variable logistic regression modeling were performed. Results: About 905 patients were included in the analysis—175 (19.3%) were male and 730 (80.7%) were female. Males were more likely to sustain perioperative complications (26.3% vs. 14.1%; P < .001)—pneumonia (2.9% vs. 0.5%; P = .016), unplanned intubation (2.3% vs. 0.4%; P = .029), and unplanned reoperation (9.1% vs. 1.1%; P < .001). On multivariate analysis, males were at a 2.4-fold increase risk of developing any complication (OR = 2.38 [95% CI 1.55-3.65]; P < .001) and a 10-fold increase risk of returning to the operating room for an unplanned reoperation (OR = 10.59 [95% CI 4.23-27.49]; P < .001) compared with females. Conclusion: Females were more likely to undergo reverse shoulder arthroplasty for proximal humerus fracture, but males were at increased risk of sustaining short-term complications. This study provides useful information for clinicians to consider when counseling their patients during the perioperative period.http://www.sciencedirect.com/science/article/pii/S2666638321000463Biological sexNational Surgical Quality Improvement Program
spellingShingle Chimere O. Ezuma, BS
Rashed L. Kosber, BA
David Kovacevic, MD
Biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fracture
JSES International
Biological sex
National Surgical Quality Improvement Program
title Biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fracture
title_full Biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fracture
title_fullStr Biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fracture
title_full_unstemmed Biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fracture
title_short Biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fracture
title_sort biological sex impacts perioperative complications after reverse shoulder arthroplasty for proximal humeral fracture
topic Biological sex
National Surgical Quality Improvement Program
url http://www.sciencedirect.com/science/article/pii/S2666638321000463
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