Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization
Several studies have been carried out to develop new materials for biomedical applications. Material surfaces that present biomimetic morphology like nanotubes or nanofibers that provides nanoscale architectures have been shown to alter cell/biomaterial interactions. The coated surface biomaterial w...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol)
2020-11-01
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| Series: | Materials Research |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392020000600209&tlng=en |
| _version_ | 1818745104737763328 |
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| author | Patricia Capellato Samira E. A. Camargo Gilbert Silva Daniela Sachs Filipe Bueno Vilela Cecilia A. de C. Zavaglia Ketul C. Popat Ana P.R. Alves Claro |
| author_facet | Patricia Capellato Samira E. A. Camargo Gilbert Silva Daniela Sachs Filipe Bueno Vilela Cecilia A. de C. Zavaglia Ketul C. Popat Ana P.R. Alves Claro |
| author_sort | Patricia Capellato |
| collection | DOAJ |
| description | Several studies have been carried out to develop new materials for biomedical applications. Material surfaces that present biomimetic morphology like nanotubes or nanofibers that provides nanoscale architectures have been shown to alter cell/biomaterial interactions. The coated surface biomaterial with biocompatible polymers and nanotubes of TiO2 is an alternative to improve osseointegration. The anodization process was performed to obtain nanotubes of TiO2 covering the Ti-30Ta alloy surface and the electrospinning process has been used for producing polymer fibers. Characterization techniques such as scanning electron microscopy (SEM - FEG), X-ray diffraction analysis (X-rays), thermogravimetric analysis (TGA), Differential Scanning Calorimetry (DSC) and contact angle were used for samples analyses. Adult human adipose-derived stem cells (ADSCs) were used to investigate the cellular response and S. aureus antimicrobial activity on these coated surfaces. The results indicated that both surface modification treatment showed a favorable micro-environment for cells growth and proliferation such as adhesion, viability and morphology which is a desire property for an implant. In addition, the antimicrobial activity study presented both materials with similar growth of S. aureus. So, it can conclude nanotubes and nanofibers can be used at biomedical field and both present similar cell evaluation and antimicrobial activity results. |
| first_indexed | 2024-12-18T02:54:54Z |
| format | Article |
| id | doaj.art-28e49da50fdf4f7080833df3bb112f28 |
| institution | Directory Open Access Journal |
| issn | 1516-1439 |
| language | English |
| last_indexed | 2024-12-18T02:54:54Z |
| publishDate | 2020-11-01 |
| publisher | Associação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol) |
| record_format | Article |
| series | Materials Research |
| spelling | doaj.art-28e49da50fdf4f7080833df3bb112f282022-12-21T21:23:23ZengAssociação Brasileira de Metalurgia e Materiais (ABM); Associação Brasileira de Cerâmica (ABC); Associação Brasileira de Polímeros (ABPol)Materials Research1516-14392020-11-0123610.1590/1980-5373-mr-2020-0305Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro CharacterizationPatricia Capellatohttps://orcid.org/0000-0002-6397-5820Samira E. A. CamargoGilbert SilvaDaniela SachsFilipe Bueno VilelaCecilia A. de C. ZavagliaKetul C. PopatAna P.R. Alves ClaroSeveral studies have been carried out to develop new materials for biomedical applications. Material surfaces that present biomimetic morphology like nanotubes or nanofibers that provides nanoscale architectures have been shown to alter cell/biomaterial interactions. The coated surface biomaterial with biocompatible polymers and nanotubes of TiO2 is an alternative to improve osseointegration. The anodization process was performed to obtain nanotubes of TiO2 covering the Ti-30Ta alloy surface and the electrospinning process has been used for producing polymer fibers. Characterization techniques such as scanning electron microscopy (SEM - FEG), X-ray diffraction analysis (X-rays), thermogravimetric analysis (TGA), Differential Scanning Calorimetry (DSC) and contact angle were used for samples analyses. Adult human adipose-derived stem cells (ADSCs) were used to investigate the cellular response and S. aureus antimicrobial activity on these coated surfaces. The results indicated that both surface modification treatment showed a favorable micro-environment for cells growth and proliferation such as adhesion, viability and morphology which is a desire property for an implant. In addition, the antimicrobial activity study presented both materials with similar growth of S. aureus. So, it can conclude nanotubes and nanofibers can be used at biomedical field and both present similar cell evaluation and antimicrobial activity results.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392020000600209&tlng=enBiocompatible polymersTitanium alloyTiO2 nanotubeCell responseNanofibers |
| spellingShingle | Patricia Capellato Samira E. A. Camargo Gilbert Silva Daniela Sachs Filipe Bueno Vilela Cecilia A. de C. Zavaglia Ketul C. Popat Ana P.R. Alves Claro Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization Materials Research Biocompatible polymers Titanium alloy TiO2 nanotube Cell response Nanofibers |
| title | Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization |
| title_full | Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization |
| title_fullStr | Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization |
| title_full_unstemmed | Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization |
| title_short | Coated Surface on Ti-30Ta Alloy for Biomedical Application: Mechanical and in-vitro Characterization |
| title_sort | coated surface on ti 30ta alloy for biomedical application mechanical and in vitro characterization |
| topic | Biocompatible polymers Titanium alloy TiO2 nanotube Cell response Nanofibers |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-14392020000600209&tlng=en |
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