Treatment of Pulmonary Embolism: a Decade of Experience
Pulmonary embolism (PE) is a major life-threatening illness which remains one of the main causes of sudden death throughout the world. The analysis of diagnosis and treatment of 472 patients with acute pulmonary embolism for a period of 10 years was performed. High efficiency of diagnosis using mult...
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Format: | Article |
Language: | English |
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Professional Edition Eastern Europe
2019-05-01
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Series: | Український журнал серцево-судинної хірургії |
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Online Access: | http://cvs.org.ua/index.php/ujcvs/article/view/115 |
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author | A. Nikonenko A. Nikonenko S. Matvieiev V. Osaulenko S. Nakonechniy |
author_facet | A. Nikonenko A. Nikonenko S. Matvieiev V. Osaulenko S. Nakonechniy |
author_sort | A. Nikonenko |
collection | DOAJ |
description | Pulmonary embolism (PE) is a major life-threatening illness which remains one of the main causes of sudden death throughout the world. The analysis of diagnosis and treatment of 472 patients with acute pulmonary embolism for a period of 10 years was performed. High efficiency of diagnosis using multispiral computer angiopulmonography (MSCT APG) has been established, thus this method completely supersedes the traditional selective angiopulmonography.
Seventeen (3.6 %) patients died due to PE recurrence, another 8 (1.7 %) patients died due to the bleeding after using fibrinolytics and anticoagulants, and 14 (2.9 %) died due to progression of organs failure. This emphasizes the need to improve measures aimed to prevent PE recurrence and identify sources of possible bleeding and refrain from aggressive fibrinolytic therapy.
The use of differentiated approach to the treatment with thrombolytic therapy and anticoagulants enabled to achieve recovery in 433 (91.7 %) patients who were discharged for outpatient treatment. New oral anticoagulants were prescribed to 94 (21.7 %) patients after discharge. |
first_indexed | 2024-12-19T02:36:00Z |
format | Article |
id | doaj.art-28eb6510fe444e4aa24db6ebe3023b98 |
institution | Directory Open Access Journal |
issn | 2664-5963 2664-5971 |
language | English |
last_indexed | 2024-12-19T02:36:00Z |
publishDate | 2019-05-01 |
publisher | Professional Edition Eastern Europe |
record_format | Article |
series | Український журнал серцево-судинної хірургії |
spelling | doaj.art-28eb6510fe444e4aa24db6ebe3023b982022-12-21T20:39:23ZengProfessional Edition Eastern EuropeУкраїнський журнал серцево-судинної хірургії2664-59632664-59712019-05-012 (35)464910.30702/ujcvs/19.3505/038046-049115Treatment of Pulmonary Embolism: a Decade of ExperienceA. Nikonenko0A. Nikonenko1S. Matvieiev2V. Osaulenko3S. Nakonechniy4Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine, Zaporizhzhia, Ukraine; Zaporizhzhia State Medical University, Zaporizhzhia, UkraineZaporizhzhia State Medical University, Zaporizhzhia, UkraineZaporizhzhia State Medical University, Zaporizhzhia, Ukraine; Zaporizhzhia Regional Clinical Hospital, Zaporizhzhia, UkraineZaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine, Zaporizhzhia, Ukraine; Zaporizhzhia Regional Clinical Hospital, Zaporizhzhia, UkraineZaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine, Zaporizhzhia, Ukraine; Zaporizhzhia Regional Clinical Hospital, Zaporizhzhia, UkrainePulmonary embolism (PE) is a major life-threatening illness which remains one of the main causes of sudden death throughout the world. The analysis of diagnosis and treatment of 472 patients with acute pulmonary embolism for a period of 10 years was performed. High efficiency of diagnosis using multispiral computer angiopulmonography (MSCT APG) has been established, thus this method completely supersedes the traditional selective angiopulmonography. Seventeen (3.6 %) patients died due to PE recurrence, another 8 (1.7 %) patients died due to the bleeding after using fibrinolytics and anticoagulants, and 14 (2.9 %) died due to progression of organs failure. This emphasizes the need to improve measures aimed to prevent PE recurrence and identify sources of possible bleeding and refrain from aggressive fibrinolytic therapy. The use of differentiated approach to the treatment with thrombolytic therapy and anticoagulants enabled to achieve recovery in 433 (91.7 %) patients who were discharged for outpatient treatment. New oral anticoagulants were prescribed to 94 (21.7 %) patients after discharge.http://cvs.org.ua/index.php/ujcvs/article/view/115pulmonary embolismcomputer tomographyanticoagulantsthrombolysisrecurrent pulmonary embolism |
spellingShingle | A. Nikonenko A. Nikonenko S. Matvieiev V. Osaulenko S. Nakonechniy Treatment of Pulmonary Embolism: a Decade of Experience Український журнал серцево-судинної хірургії pulmonary embolism computer tomography anticoagulants thrombolysis recurrent pulmonary embolism |
title | Treatment of Pulmonary Embolism: a Decade of Experience |
title_full | Treatment of Pulmonary Embolism: a Decade of Experience |
title_fullStr | Treatment of Pulmonary Embolism: a Decade of Experience |
title_full_unstemmed | Treatment of Pulmonary Embolism: a Decade of Experience |
title_short | Treatment of Pulmonary Embolism: a Decade of Experience |
title_sort | treatment of pulmonary embolism a decade of experience |
topic | pulmonary embolism computer tomography anticoagulants thrombolysis recurrent pulmonary embolism |
url | http://cvs.org.ua/index.php/ujcvs/article/view/115 |
work_keys_str_mv | AT anikonenko treatmentofpulmonaryembolismadecadeofexperience AT anikonenko treatmentofpulmonaryembolismadecadeofexperience AT smatvieiev treatmentofpulmonaryembolismadecadeofexperience AT vosaulenko treatmentofpulmonaryembolismadecadeofexperience AT snakonechniy treatmentofpulmonaryembolismadecadeofexperience |