Treatment of Pulmonary Embolism: a Decade of Experience

Pulmonary embolism (PE) is a major life-threatening illness which remains one of the main causes of sudden death throughout the world. The analysis of diagnosis and treatment of 472 patients with acute pulmonary embolism for a period of 10 years was performed. High efficiency of diagnosis using mult...

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Main Authors: A. Nikonenko, S. Matvieiev, V. Osaulenko, S. Nakonechniy
Format: Article
Language:English
Published: Professional Edition Eastern Europe 2019-05-01
Series:Український журнал серцево-судинної хірургії
Subjects:
Online Access:http://cvs.org.ua/index.php/ujcvs/article/view/115
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author A. Nikonenko
A. Nikonenko
S. Matvieiev
V. Osaulenko
S. Nakonechniy
author_facet A. Nikonenko
A. Nikonenko
S. Matvieiev
V. Osaulenko
S. Nakonechniy
author_sort A. Nikonenko
collection DOAJ
description Pulmonary embolism (PE) is a major life-threatening illness which remains one of the main causes of sudden death throughout the world. The analysis of diagnosis and treatment of 472 patients with acute pulmonary embolism for a period of 10 years was performed. High efficiency of diagnosis using multispiral computer angiopulmonography (MSCT APG) has been established, thus this method completely supersedes the traditional selective angiopulmonography. Seventeen (3.6 %) patients died due to PE recurrence, another 8 (1.7 %) patients died due to the bleeding after using fibrinolytics and anticoagulants, and 14 (2.9 %) died due to progression of organs failure. This emphasizes the need to improve measures aimed to prevent PE recurrence and identify sources of possible bleeding and refrain from aggressive fibrinolytic therapy. The use of differentiated approach to the treatment with thrombolytic therapy and anticoagulants enabled to achieve recovery in 433 (91.7 %) patients who were discharged for outpatient treatment. New oral anticoagulants were prescribed to 94 (21.7 %) patients after discharge.
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spelling doaj.art-28eb6510fe444e4aa24db6ebe3023b982022-12-21T20:39:23ZengProfessional Edition Eastern EuropeУкраїнський журнал серцево-судинної хірургії2664-59632664-59712019-05-012 (35)464910.30702/ujcvs/19.3505/038046-049115Treatment of Pulmonary Embolism: a Decade of ExperienceA. Nikonenko0A. Nikonenko1S. Matvieiev2V. Osaulenko3S. Nakonechniy4Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine, Zaporizhzhia, Ukraine; Zaporizhzhia State Medical University, Zaporizhzhia, UkraineZaporizhzhia State Medical University, Zaporizhzhia, UkraineZaporizhzhia State Medical University, Zaporizhzhia, Ukraine; Zaporizhzhia Regional Clinical Hospital, Zaporizhzhia, UkraineZaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine, Zaporizhzhia, Ukraine; Zaporizhzhia Regional Clinical Hospital, Zaporizhzhia, UkraineZaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine, Zaporizhzhia, Ukraine; Zaporizhzhia Regional Clinical Hospital, Zaporizhzhia, UkrainePulmonary embolism (PE) is a major life-threatening illness which remains one of the main causes of sudden death throughout the world. The analysis of diagnosis and treatment of 472 patients with acute pulmonary embolism for a period of 10 years was performed. High efficiency of diagnosis using multispiral computer angiopulmonography (MSCT APG) has been established, thus this method completely supersedes the traditional selective angiopulmonography. Seventeen (3.6 %) patients died due to PE recurrence, another 8 (1.7 %) patients died due to the bleeding after using fibrinolytics and anticoagulants, and 14 (2.9 %) died due to progression of organs failure. This emphasizes the need to improve measures aimed to prevent PE recurrence and identify sources of possible bleeding and refrain from aggressive fibrinolytic therapy. The use of differentiated approach to the treatment with thrombolytic therapy and anticoagulants enabled to achieve recovery in 433 (91.7 %) patients who were discharged for outpatient treatment. New oral anticoagulants were prescribed to 94 (21.7 %) patients after discharge.http://cvs.org.ua/index.php/ujcvs/article/view/115pulmonary embolismcomputer tomographyanticoagulantsthrombolysisrecurrent pulmonary embolism
spellingShingle A. Nikonenko
A. Nikonenko
S. Matvieiev
V. Osaulenko
S. Nakonechniy
Treatment of Pulmonary Embolism: a Decade of Experience
Український журнал серцево-судинної хірургії
pulmonary embolism
computer tomography
anticoagulants
thrombolysis
recurrent pulmonary embolism
title Treatment of Pulmonary Embolism: a Decade of Experience
title_full Treatment of Pulmonary Embolism: a Decade of Experience
title_fullStr Treatment of Pulmonary Embolism: a Decade of Experience
title_full_unstemmed Treatment of Pulmonary Embolism: a Decade of Experience
title_short Treatment of Pulmonary Embolism: a Decade of Experience
title_sort treatment of pulmonary embolism a decade of experience
topic pulmonary embolism
computer tomography
anticoagulants
thrombolysis
recurrent pulmonary embolism
url http://cvs.org.ua/index.php/ujcvs/article/view/115
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AT smatvieiev treatmentofpulmonaryembolismadecadeofexperience
AT vosaulenko treatmentofpulmonaryembolismadecadeofexperience
AT snakonechniy treatmentofpulmonaryembolismadecadeofexperience