Structure–Activity Relationship Studies of 9-Alkylamino-1,2,3,4-tetrahydroacridines against <i>Leishmania</i> (<i>Leishmania</i>) <i>infantum</i> Promastigotes

Structure–Activity Relationship Studies of 9-Alkylamino-1,2,3,4-tetrahydroacridines against <i>Leishmania</i> (<i>Leishmania</i>) <i>infantum</i> Promastigotes

Leishmaniasis is one of the most neglected diseases in modern times, mainly affecting people from developing countries of the tropics, subtropics and the Mediterranean basin, with approximately 350 million people considered at risk of developing this disease. The incidence of human leishmaniasis has...

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Bibliographic Details
Main Authors: Carlos F. M. Silva, Teresa Leão, Filipa Dias, Ana M. Tomás, Diana C. G. A. Pinto, Eduardo F. T. Oliveira, Ana Oliveira, Pedro A. Fernandes, Artur M. S. Silva
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
<i>Leishmania</i>
virtual screening
AdoMet DC
microwave-assisted synthesis
1,2,3,4-tetrahydroacridine
quinoline
Online Access:https://www.mdpi.com/1999-4923/15/2/669

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