Rhus coriaria L. (Sumac) Evokes Endothelium-Dependent Vasorelaxation of Rat Aorta: Involvement of the cAMP and cGMP Pathways

Rhus coriaria L. (Sumac) Evokes Endothelium-Dependent Vasorelaxation of Rat Aorta: Involvement of the cAMP and cGMP Pathways

Rhus coriaria L. (sumac) is widely used in traditional remedies and cuisine of countries of the Mediterranean as well as Central and South-West Asia. Administration of sumac to experimental models and patients with diverse pathological conditions generates multi-faceted propitious effects, including...

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Bibliographic Details
Main Authors: Mohammad A. Anwar, Ali A. Samaha, Safaa Baydoun, Rabah Iratni, Ali H. Eid
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
Rhus coriaria
sumac
endothelium-dependent relaxation
phosphoinositide 3-kinase (PI3K)
Akt
endothelial nitric oxide synthase (eNOS)
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00688/full

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