Tratamento cirúrgico do hiperparatiroidismo primário com PTHi intra-operatória.
Primary hyperparathyroidism (pHPT) is most frequently caused by a solitary adenoma. Surgical intervention has a high cure rate, particularly when associated with a fast intraoperative intact parathyroid hormone (IOPTH) assay. Aim: to evaluate the performance and accuracy when applying this technique...
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| Format: | Article |
| Language: | English |
| Published: |
Ordem dos Médicos
2008-04-01
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| Series: | Acta Médica Portuguesa |
| Online Access: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/763 |
| _version_ | 1817980001064058880 |
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| author | Miguel Allen Isabel Almeida Joaquim Torrinha |
| author_facet | Miguel Allen Isabel Almeida Joaquim Torrinha |
| author_sort | Miguel Allen |
| collection | DOAJ |
| description | Primary hyperparathyroidism (pHPT) is most frequently caused by a solitary adenoma. Surgical intervention has a high cure rate, particularly when associated with a fast intraoperative intact parathyroid hormone (IOPTH) assay. Aim: to evaluate the performance and accuracy when applying this technique.we conducted a retrospective study of the last 20 patients with pHPT (mean age 59, range 24-75) that had a surgical intervention in our unit. IOPTH was used in 14 patients, with dosage at 5, 10, 15 and 30 minutes after removal of the adenoma.The localization exams had a sensitivity of >75%. The surgical procedure of choice was a unilateral dissection through a 4cm central mini-incision, with all patients experiencing a reduction of >50% of the IOPTH at 10 minutes. There were no surgical complications and the average length of the follow-up period was 11.4 months. The mean calcemia and iPTH dosage progression, from pre-surgery to the last follow-up visit, was respectively of 11 (SD1) to 9.4 (SD0.5) mg/dl and of 233.3 (SD177.5) to 57.1 (SD42) pg/ml. Symptoms improved in all patients. |
| first_indexed | 2024-04-13T22:48:09Z |
| format | Article |
| id | doaj.art-28f7cd834ab94f21a8f923645a6511c1 |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-13T22:48:09Z |
| publishDate | 2008-04-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-28f7cd834ab94f21a8f923645a6511c12022-12-22T02:26:17ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582008-04-0121110.20344/amp.763Tratamento cirúrgico do hiperparatiroidismo primário com PTHi intra-operatória.Miguel Allen0Isabel AlmeidaJoaquim TorrinhaServiço de Cirurgia II, Hospital de Egas Moniz, Lisboa.Primary hyperparathyroidism (pHPT) is most frequently caused by a solitary adenoma. Surgical intervention has a high cure rate, particularly when associated with a fast intraoperative intact parathyroid hormone (IOPTH) assay. Aim: to evaluate the performance and accuracy when applying this technique.we conducted a retrospective study of the last 20 patients with pHPT (mean age 59, range 24-75) that had a surgical intervention in our unit. IOPTH was used in 14 patients, with dosage at 5, 10, 15 and 30 minutes after removal of the adenoma.The localization exams had a sensitivity of >75%. The surgical procedure of choice was a unilateral dissection through a 4cm central mini-incision, with all patients experiencing a reduction of >50% of the IOPTH at 10 minutes. There were no surgical complications and the average length of the follow-up period was 11.4 months. The mean calcemia and iPTH dosage progression, from pre-surgery to the last follow-up visit, was respectively of 11 (SD1) to 9.4 (SD0.5) mg/dl and of 233.3 (SD177.5) to 57.1 (SD42) pg/ml. Symptoms improved in all patients.https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/763 |
| spellingShingle | Miguel Allen Isabel Almeida Joaquim Torrinha Tratamento cirúrgico do hiperparatiroidismo primário com PTHi intra-operatória. Acta Médica Portuguesa |
| title | Tratamento cirúrgico do hiperparatiroidismo primário com PTHi intra-operatória. |
| title_full | Tratamento cirúrgico do hiperparatiroidismo primário com PTHi intra-operatória. |
| title_fullStr | Tratamento cirúrgico do hiperparatiroidismo primário com PTHi intra-operatória. |
| title_full_unstemmed | Tratamento cirúrgico do hiperparatiroidismo primário com PTHi intra-operatória. |
| title_short | Tratamento cirúrgico do hiperparatiroidismo primário com PTHi intra-operatória. |
| title_sort | tratamento cirurgico do hiperparatiroidismo primario com pthi intra operatoria |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/763 |
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