Standardized programming to reduce the burden of inappropriate therapies in implantable cardioverter defibrillators - Single centre follow up results

Background: Current algorithms and device morphology templates have been proposed in current Implantable Cardioverter-Defibrillators (ICDs) to minimize inappropriate therapies (ITS), but this has not been completely successful. Aim: Assess the impact of a deliberate strategy of using an atrial lead...

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Main Authors: U. Boles, E.E. Gul, L. Fitzgerald, F. Sadiq Ali, C. Nolan, K. Aldworth-Gaumond, D.R. Redfearn, A. Baranchuk, B. Glover, C. Simpson, H. Abdollah, K.A. Michael
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Indian Pacing and Electrophysiology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S097262921730133X
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author U. Boles
E.E. Gul
L. Fitzgerald
F. Sadiq Ali
C. Nolan
K. Aldworth-Gaumond
D.R. Redfearn
A. Baranchuk
B. Glover
C. Simpson
H. Abdollah
K.A. Michael
author_facet U. Boles
E.E. Gul
L. Fitzgerald
F. Sadiq Ali
C. Nolan
K. Aldworth-Gaumond
D.R. Redfearn
A. Baranchuk
B. Glover
C. Simpson
H. Abdollah
K.A. Michael
author_sort U. Boles
collection DOAJ
description Background: Current algorithms and device morphology templates have been proposed in current Implantable Cardioverter-Defibrillators (ICDs) to minimize inappropriate therapies (ITS), but this has not been completely successful. Aim: Assess the impact of a deliberate strategy of using an atrial lead implant with standardized parameters; based on all current ICD discriminators and technologies, on the burden of ITS. Method: A retrospective single-centre analysis of 250 patients with either dual chamber (DR) ICDs or biventricular ICDs (CRTDs) over a (41.9 ± 27.3) month period was performed. The incidence of ITS on all ICD and CRTD patients was chronicled after the implementation of standardized programming. Results: 39 events of anti-tachycardial pacing (ATP) and/or shocks were identified in 20 patients (8% incidence rate among patients). The total number of individual therapies was 120, of which 34% were inappropriate ATP, and 36% were inappropriate shocks. 11 patients of the 250 patients received ITS (4.4%). Of the 20 patients, four had ICDs for primary prevention and 16 for a secondary prevention. All the episodes in the primary indication group were inappropriate, while seven patients (43%) of the secondary indication group experienced inappropriate therapies. Conclusions: The burden of ITS in the population of patients receiving ICDs was 4.4% in the presence of atrial leads. The proposed rationalized programming criteria seems an effective strategy to minimize the burden of inappropriate therapies and will require further validation. Keywords: Implantable cardioverter-defibrillator (ICDs), Inappropriate therapies, Standardized programming
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spelling doaj.art-28f842c56cbb4fdb9fd2918df86731d12022-12-21T23:59:06ZengElsevierIndian Pacing and Electrophysiology Journal0972-62922018-03-011825660Standardized programming to reduce the burden of inappropriate therapies in implantable cardioverter defibrillators - Single centre follow up resultsU. Boles0E.E. Gul1L. Fitzgerald2F. Sadiq Ali3C. Nolan4K. Aldworth-Gaumond5D.R. Redfearn6A. Baranchuk7B. Glover8C. Simpson9H. Abdollah10K.A. Michael11Heart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, Canada; Cardiology Department, Midland Regional Hospital Mullingar (MRHM), Ireland; Corresponding author. Heart and Vascular Department, Mater Private Hospital, Dublin, Ireland.Heart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, CanadaCardiology Department, Midland Regional Hospital Mullingar (MRHM), IrelandHeart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, CanadaHeart and Vascular Centre, Mater Private Hospital, Dublin, IrelandHeart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, CanadaHeart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, CanadaHeart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, CanadaHeart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, CanadaHeart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, CanadaHeart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, CanadaHeart Rhythm Service, Division of Cardiology, Kingston General Hospital, Queen's University, Ontario, CanadaBackground: Current algorithms and device morphology templates have been proposed in current Implantable Cardioverter-Defibrillators (ICDs) to minimize inappropriate therapies (ITS), but this has not been completely successful. Aim: Assess the impact of a deliberate strategy of using an atrial lead implant with standardized parameters; based on all current ICD discriminators and technologies, on the burden of ITS. Method: A retrospective single-centre analysis of 250 patients with either dual chamber (DR) ICDs or biventricular ICDs (CRTDs) over a (41.9 ± 27.3) month period was performed. The incidence of ITS on all ICD and CRTD patients was chronicled after the implementation of standardized programming. Results: 39 events of anti-tachycardial pacing (ATP) and/or shocks were identified in 20 patients (8% incidence rate among patients). The total number of individual therapies was 120, of which 34% were inappropriate ATP, and 36% were inappropriate shocks. 11 patients of the 250 patients received ITS (4.4%). Of the 20 patients, four had ICDs for primary prevention and 16 for a secondary prevention. All the episodes in the primary indication group were inappropriate, while seven patients (43%) of the secondary indication group experienced inappropriate therapies. Conclusions: The burden of ITS in the population of patients receiving ICDs was 4.4% in the presence of atrial leads. The proposed rationalized programming criteria seems an effective strategy to minimize the burden of inappropriate therapies and will require further validation. Keywords: Implantable cardioverter-defibrillator (ICDs), Inappropriate therapies, Standardized programminghttp://www.sciencedirect.com/science/article/pii/S097262921730133X
spellingShingle U. Boles
E.E. Gul
L. Fitzgerald
F. Sadiq Ali
C. Nolan
K. Aldworth-Gaumond
D.R. Redfearn
A. Baranchuk
B. Glover
C. Simpson
H. Abdollah
K.A. Michael
Standardized programming to reduce the burden of inappropriate therapies in implantable cardioverter defibrillators - Single centre follow up results
Indian Pacing and Electrophysiology Journal
title Standardized programming to reduce the burden of inappropriate therapies in implantable cardioverter defibrillators - Single centre follow up results
title_full Standardized programming to reduce the burden of inappropriate therapies in implantable cardioverter defibrillators - Single centre follow up results
title_fullStr Standardized programming to reduce the burden of inappropriate therapies in implantable cardioverter defibrillators - Single centre follow up results
title_full_unstemmed Standardized programming to reduce the burden of inappropriate therapies in implantable cardioverter defibrillators - Single centre follow up results
title_short Standardized programming to reduce the burden of inappropriate therapies in implantable cardioverter defibrillators - Single centre follow up results
title_sort standardized programming to reduce the burden of inappropriate therapies in implantable cardioverter defibrillators single centre follow up results
url http://www.sciencedirect.com/science/article/pii/S097262921730133X
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