Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species
Candida auris is an emergent fungal pathogen that is resistant to multiple antifungals. Here, Muñoz et al. analyse genomic sequences for isolates from each of the four major C. auris clades and for three related species, and identify genetic features associated with virulence, antifungal resistance...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-07779-6 |
| _version_ | 1818842249612492800 |
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| author | José F. Muñoz Lalitha Gade Nancy A. Chow Vladimir N. Loparev Phalasy Juieng Elizabeth L. Berkow Rhys A. Farrer Anastasia P. Litvintseva Christina A. Cuomo |
| author_facet | José F. Muñoz Lalitha Gade Nancy A. Chow Vladimir N. Loparev Phalasy Juieng Elizabeth L. Berkow Rhys A. Farrer Anastasia P. Litvintseva Christina A. Cuomo |
| author_sort | José F. Muñoz |
| collection | DOAJ |
| description | Candida auris is an emergent fungal pathogen that is resistant to multiple antifungals. Here, Muñoz et al. analyse genomic sequences for isolates from each of the four major C. auris clades and for three related species, and identify genetic features associated with virulence, antifungal resistance and mating. |
| first_indexed | 2024-12-19T04:38:59Z |
| format | Article |
| id | doaj.art-28fad645359b4b4b9e6b3f364031c465 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T04:38:59Z |
| publishDate | 2018-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-28fad645359b4b4b9e6b3f364031c4652022-12-21T20:35:41ZengNature PortfolioNature Communications2041-17232018-12-019111310.1038/s41467-018-07779-6Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging speciesJosé F. Muñoz0Lalitha Gade1Nancy A. Chow2Vladimir N. Loparev3Phalasy Juieng4Elizabeth L. Berkow5Rhys A. Farrer6Anastasia P. Litvintseva7Christina A. Cuomo8Broad Institute of MIT and HarvardMycotic Diseases Branch, Centers for Disease Control and PreventionMycotic Diseases Branch, Centers for Disease Control and PreventionBiotechnology Core Facility Branch, Centers for Disease Control and PreventionBiotechnology Core Facility Branch, Centers for Disease Control and PreventionMycotic Diseases Branch, Centers for Disease Control and PreventionBroad Institute of MIT and HarvardMycotic Diseases Branch, Centers for Disease Control and PreventionBroad Institute of MIT and HarvardCandida auris is an emergent fungal pathogen that is resistant to multiple antifungals. Here, Muñoz et al. analyse genomic sequences for isolates from each of the four major C. auris clades and for three related species, and identify genetic features associated with virulence, antifungal resistance and mating.https://doi.org/10.1038/s41467-018-07779-6 |
| spellingShingle | José F. Muñoz Lalitha Gade Nancy A. Chow Vladimir N. Loparev Phalasy Juieng Elizabeth L. Berkow Rhys A. Farrer Anastasia P. Litvintseva Christina A. Cuomo Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species Nature Communications |
| title | Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species |
| title_full | Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species |
| title_fullStr | Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species |
| title_full_unstemmed | Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species |
| title_short | Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species |
| title_sort | genomic insights into multidrug resistance mating and virulence in candida auris and related emerging species |
| url | https://doi.org/10.1038/s41467-018-07779-6 |
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