The Optimization of the Synthesis Process and the Identification of Levobupivacaine Hydrochloride

The Optimization of the Synthesis Process and the Identification of Levobupivacaine Hydrochloride

In this study, we not only optimized and improved the synthesis process of levobupivacaine hydrochloride (<b>21</b>) but also conducted a comprehensive exploration of critical industrial-scale production details, and a novel high-performance liquid chromatography (HPLC) analysis method w...

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Bibliographic Details
Main Authors:	Qiuming Yan, Houjun Gan, Chunzheng Li, Gang Gui, Jianbo Wang, Xiaoming Zha
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	Molecules
Subjects:	levobupivacaine hydrochloride local anesthetic synthesis chiral separation crystal structure process improvement
Online Access:	https://www.mdpi.com/1420-3049/28/22/7482

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