DNA Methylation Levels of the <i>TBX5</i> Gene Promoter Are Associated with Congenital Septal Defects in Mexican Paediatric Patients

DNA Methylation Levels of the <i>TBX5</i> Gene Promoter Are Associated with Congenital Septal Defects in Mexican Paediatric Patients

The <i>TBX5</i> gene regulates morphological changes during heart development, and it has been associated with epigenetic abnormalities observed in congenital heart defects (CHD). The aim of this research was to evaluate the association between DNA methylation levels of the <i>TBX5...

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Main Authors: Esbeidy García-Flores, José Manuel Rodríguez-Pérez, Verónica Marusa Borgonio-Cuadra, Gilberto Vargas-Alarcón, Juan Calderón-Colmenero, Juan Pablo Sandoval, José Antonio García-Montes, Víctor Manuel Espinoza-Gutiérrez, Juan Gerardo Reyes-García, Benny Giovanni Cazarín-Santos, Antonio Miranda-Duarte, Armando Gamboa-Domínguez, Nonanzit Pérez-Hernández
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biology
Subjects:
congenital septal defects
DNA methylation
<i>TBX5</i> gene
epigenetic markers
transcriptional factors
Online Access:https://www.mdpi.com/2079-7737/11/1/96

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