An Indian perspective on primary angle closure and glaucoma

<b>Aim:</b> To provide a synopsis of primary angle closure disease in India, and Indian studies on the same. <b>Results:</b> Primary angle closure glaucoma forms almost half of all adult primary glaucomas seen in a hospital setting in India. Anatomically, corneal diameters a...

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Bibliographic Details
Main Author: Sihota Ramanjit
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-12-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2011;volume=59;issue=7;spage=76;epage=81;aulast=Sihota
Description
Summary:<b>Aim:</b> To provide a synopsis of primary angle closure disease in India, and Indian studies on the same. <b>Results:</b> Primary angle closure glaucoma forms almost half of all adult primary glaucomas seen in a hospital setting in India. Anatomically, corneal diameters and anterior chamber depths were least in acute and chronic PACG eyes as compared to subacute eyes and controls. Besides relative pupillary block, a Valsalva maneuver during activities of daily living may be responsible for intermittent angle closure and raised IOP in predisposed eyes. Iridotomy alone, controlled the intraocular pressure in 66.7&#x0025; of subacute eyes and 12.9&#x0025; of the acute. Medical therapy was additionally required for 35.5&#x0025; of the acute eyes, 12.1&#x0025; of the subacute and 30.0&#x0025; of the chronic cases. There was a greater mean and peak IOP reduction, achieved with 0.005&#x0025; latanoprost once daily, 8.2 &#177; 2.0 mm Hg, compared with 0.5&#x0025; timolol twice daily, 6.1 &#177; 1.7 mm Hg2. A progression of PACS to PAC was seen in 22&#x0025;, PAC to PAC OHT in 38.7&#x0025; and PAC OHT to PACG in 30.7&#x0025; over 5 years. <b>Conclusions:</b> Primary angle closure disease is common in India, and can be managed well with iridotomy, followed by an appropriate control of IOP.
ISSN:0301-4738
1998-3689