Highly reproductive attenuated H2N2 and H7N9 reassortants on the basis of A/Hong Kong/1/68/162/35 donor virus

Reassortants with surface antigens from potentially pandemic A/H2N2 and A/H7N9 influenza viruses were created on the basis of attenuated and highly reproductive A/Hong Kong/1/68/162/35(H3N2) donor virus obtained in the Research institute of influenza. High reproductive activity of reassortant viruse...

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Bibliographic Details
Main Authors: I. G. Vidyaeva, M. V. Potapchuk, I. A. Repko, S. V. Petrov, L. M. Tsybalova
Format: Article
Language:English
Published: Central Research Institute for Epidemiology 2016-12-01
Series:Вопросы вирусологии
Subjects:
Online Access:https://virusjour.crie.ru/jour/article/viewFile/104/35
Description
Summary:Reassortants with surface antigens from potentially pandemic A/H2N2 and A/H7N9 influenza viruses were created on the basis of attenuated and highly reproductive A/Hong Kong/1/68/162/35(H3N2) donor virus obtained in the Research institute of influenza. High reproductive activity of reassortant viruses and immunogenicity of live and inactivated influenza vaccines based on these viruses indicate the possibility to use obtained reassortants for production of live and inactivated vaccines against potentially pandemic influenza A viruses.
ISSN:0507-4088
2411-2097