Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension
Objective - to evaluate the efficacy and safety of D-, L- hopantenic acid (pantogam active) on cognitive and anxiety disorders in patients with arterial hypertension. Material and methods. Autors selected 80 inpatients of a cardiology department with the verified diagnosis of hypertension and comorb...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation
2018-07-01
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| Series: | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
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| Online Access: | https://www.bekhterevreview.com/jour/article/view/101 |
| _version_ | 1826573096671248384 |
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| author | A. B. Smulevich B. A. Volel E. S. Ternovaya Yu. M. Nikitina |
| author_facet | A. B. Smulevich B. A. Volel E. S. Ternovaya Yu. M. Nikitina |
| author_sort | A. B. Smulevich |
| collection | DOAJ |
| description | Objective - to evaluate the efficacy and safety of D-, L- hopantenic acid (pantogam active) on cognitive and anxiety disorders in patients with arterial hypertension. Material and methods. Autors selected 80 inpatients of a cardiology department with the verified diagnosis of hypertension and comorbid cognitive and anxiety disorders (50 patients in the main group, 30 patients in the control one). All patients received standard cardiotropic hypotensive treatment. Patients of the main group received in addition pantogam active in the daily dose from 600 to 1200 mg. Psychopathological and psychometric examinations were conducted, the data were compared with the dynamics of physical parameters (ECG, ambulatory blood pressure monitoring, blood chemistry). The duration of treatment with pantogam activ was 28 days. Results. There was a significant reduction in both cognitive and anxiety disorders in the main group compared with the controls and in patients with a history of stroke. The positive dynamics was observed during the treatment period. Conclusions. Authors support the possibility of using D-, L-hopantenic acid (pantogam active) as a drug of choice with bimodal activity (nootropic and tranquilizing) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension. A rapid (in the first week) significant reduction of cognitive and anxiety disorders during the treatment with pantogam activ was noted. |
| first_indexed | 2024-03-12T02:57:50Z |
| format | Article |
| id | doaj.art-2905a49defa54cef94565fbd7738136c |
| institution | Directory Open Access Journal |
| issn | 2313-7053 2713-055X |
| language | Russian |
| last_indexed | 2025-03-14T12:37:29Z |
| publishDate | 2018-07-01 |
| publisher | Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation |
| record_format | Article |
| series | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
| spelling | doaj.art-2905a49defa54cef94565fbd7738136c2025-03-02T09:12:42ZrusFederal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian FederationОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева2313-70532713-055X2018-07-010396108101Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertensionA. B. Smulevich0B. A. Volel1E. S. Ternovaya2Yu. M. Nikitina3Sechenov First Moscow State Medical University; Research Center of Mental HealthSechenov First Moscow State Medical University; Research Center of Mental HealthSechenov First Moscow State Medical UniversitySechenov First Moscow State Medical UniversityObjective - to evaluate the efficacy and safety of D-, L- hopantenic acid (pantogam active) on cognitive and anxiety disorders in patients with arterial hypertension. Material and methods. Autors selected 80 inpatients of a cardiology department with the verified diagnosis of hypertension and comorbid cognitive and anxiety disorders (50 patients in the main group, 30 patients in the control one). All patients received standard cardiotropic hypotensive treatment. Patients of the main group received in addition pantogam active in the daily dose from 600 to 1200 mg. Psychopathological and psychometric examinations were conducted, the data were compared with the dynamics of physical parameters (ECG, ambulatory blood pressure monitoring, blood chemistry). The duration of treatment with pantogam activ was 28 days. Results. There was a significant reduction in both cognitive and anxiety disorders in the main group compared with the controls and in patients with a history of stroke. The positive dynamics was observed during the treatment period. Conclusions. Authors support the possibility of using D-, L-hopantenic acid (pantogam active) as a drug of choice with bimodal activity (nootropic and tranquilizing) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension. A rapid (in the first week) significant reduction of cognitive and anxiety disorders during the treatment with pantogam activ was noted.https://www.bekhterevreview.com/jour/article/view/101соматопсихиатриякогнитивные нарушениятревожные расстройстваартериальная гипертензиялечениеsomatopsychiatrycognitive impairmentanxiety disordersarterial hipertensiontreatment |
| spellingShingle | A. B. Smulevich B. A. Volel E. S. Ternovaya Yu. M. Nikitina Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева соматопсихиатрия когнитивные нарушения тревожные расстройства артериальная гипертензия лечение somatopsychiatry cognitive impairment anxiety disorders arterial hipertension treatment |
| title | Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension |
| title_full | Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension |
| title_fullStr | Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension |
| title_full_unstemmed | Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension |
| title_short | Pantogam activ (D-, L-hopantenic acid) in the treatment of cognitive and anxiety disorders in patients with arterial hypertension |
| title_sort | pantogam activ d l hopantenic acid in the treatment of cognitive and anxiety disorders in patients with arterial hypertension |
| topic | соматопсихиатрия когнитивные нарушения тревожные расстройства артериальная гипертензия лечение somatopsychiatry cognitive impairment anxiety disorders arterial hipertension treatment |
| url | https://www.bekhterevreview.com/jour/article/view/101 |
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