Future Research Directions in the Design of Versatile Extracellular Matrix in Tissue Engineering
Native and artificial extracellular matrices (ECMs) have been widely applied in biomedical fields as one of the most effective components in tissue regeneration. In particular, ECM-based drugs are expected to be applied to treat diseases in organs relevant to urology, because tissue regeneration is...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Continence Society
2018-07-01
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| Series: | International Neurourology Journal |
| Subjects: | |
| Online Access: | http://www.einj.org/upload/pdf/inj-1836154-077.pdf |
| _version_ | 1811273840023568384 |
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| author | Agustina Setiawati Huong Thanh Nguyen Yeongheon Jung Kwanwoo Shin |
| author_facet | Agustina Setiawati Huong Thanh Nguyen Yeongheon Jung Kwanwoo Shin |
| author_sort | Agustina Setiawati |
| collection | DOAJ |
| description | Native and artificial extracellular matrices (ECMs) have been widely applied in biomedical fields as one of the most effective components in tissue regeneration. In particular, ECM-based drugs are expected to be applied to treat diseases in organs relevant to urology, because tissue regeneration is particularly important for preventing the recurrence of these diseases. Native ECMs provide a complex in vivo architecture and native physical and mechanical properties that support high biocompatibility. However, the applications of native ECMs are limited due to their tissue-specificity and chemical complexity. Artificial ECMs have been fabricated in an attempt to create a broadly applicable scaffold by using controllable components and a uniform formulation. On the other hands, artificial ECMs fail to mimic the properties of a native ECM; consequently, their applications in tissues are also limited. For that reason, the design of a versatile, hybrid ECM that can be universally applied to various tissues is an emerging area of interest in the biomedical field. |
| first_indexed | 2024-04-12T23:06:42Z |
| format | Article |
| id | doaj.art-2906eb0291884d729ec60aa02c1795f8 |
| institution | Directory Open Access Journal |
| issn | 2093-4777 2093-6931 |
| language | English |
| last_indexed | 2024-04-12T23:06:42Z |
| publishDate | 2018-07-01 |
| publisher | Korean Continence Society |
| record_format | Article |
| series | International Neurourology Journal |
| spelling | doaj.art-2906eb0291884d729ec60aa02c1795f82022-12-22T03:12:53ZengKorean Continence SocietyInternational Neurourology Journal2093-47772093-69312018-07-0122Suppl 2S667510.5213/inj.1836154.077733Future Research Directions in the Design of Versatile Extracellular Matrix in Tissue EngineeringAgustina Setiawati0Huong Thanh Nguyen1Yeongheon Jung2Kwanwoo Shin3 Department of Chemistry and Institute of Biological Interfaces, Sogang University, Seoul, Korea Department of Chemistry and Institute of Biological Interfaces, Sogang University, Seoul, Korea Department of Chemistry and Institute of Biological Interfaces, Sogang University, Seoul, Korea Department of Chemistry and Institute of Biological Interfaces, Sogang University, Seoul, KoreaNative and artificial extracellular matrices (ECMs) have been widely applied in biomedical fields as one of the most effective components in tissue regeneration. In particular, ECM-based drugs are expected to be applied to treat diseases in organs relevant to urology, because tissue regeneration is particularly important for preventing the recurrence of these diseases. Native ECMs provide a complex in vivo architecture and native physical and mechanical properties that support high biocompatibility. However, the applications of native ECMs are limited due to their tissue-specificity and chemical complexity. Artificial ECMs have been fabricated in an attempt to create a broadly applicable scaffold by using controllable components and a uniform formulation. On the other hands, artificial ECMs fail to mimic the properties of a native ECM; consequently, their applications in tissues are also limited. For that reason, the design of a versatile, hybrid ECM that can be universally applied to various tissues is an emerging area of interest in the biomedical field.http://www.einj.org/upload/pdf/inj-1836154-077.pdfExtracellular matrixTissue regenerationVersatile extracellular matrixUrology |
| spellingShingle | Agustina Setiawati Huong Thanh Nguyen Yeongheon Jung Kwanwoo Shin Future Research Directions in the Design of Versatile Extracellular Matrix in Tissue Engineering International Neurourology Journal Extracellular matrix Tissue regeneration Versatile extracellular matrix Urology |
| title | Future Research Directions in the Design of Versatile Extracellular Matrix in Tissue Engineering |
| title_full | Future Research Directions in the Design of Versatile Extracellular Matrix in Tissue Engineering |
| title_fullStr | Future Research Directions in the Design of Versatile Extracellular Matrix in Tissue Engineering |
| title_full_unstemmed | Future Research Directions in the Design of Versatile Extracellular Matrix in Tissue Engineering |
| title_short | Future Research Directions in the Design of Versatile Extracellular Matrix in Tissue Engineering |
| title_sort | future research directions in the design of versatile extracellular matrix in tissue engineering |
| topic | Extracellular matrix Tissue regeneration Versatile extracellular matrix Urology |
| url | http://www.einj.org/upload/pdf/inj-1836154-077.pdf |
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