The Effect of Preoperative Neutrophil-Lymphocyte Ratio on Disease Specific Survival in Testicular Tumor Patients
INTRODUCTION: The effect of hemogram parameters on survival has been evaluated in many studies for patients who have urogenital tumor. In this study, we aimed to evaluate the neutrophil-lymphocyte ratio (NLR) on disease specific survival (DSS) in patients who have testicular tumor. METHODS: The dat...
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| Format: | Article |
| Language: | English |
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Van Yuzuncu Yil University, School of Medicine
2017-05-01
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| Series: | Van Tıp Dergisi |
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| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-75537 |
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| author | Nurullah Hamidi Evren Süer Mehmet İlker Gökçe Yaşar Bedük |
| author_facet | Nurullah Hamidi Evren Süer Mehmet İlker Gökçe Yaşar Bedük |
| author_sort | Nurullah Hamidi |
| collection | DOAJ |
| description | INTRODUCTION: The effect of hemogram parameters on survival has been evaluated in many studies for patients who have urogenital tumor. In this study, we aimed to evaluate the neutrophil-lymphocyte ratio (NLR) on disease specific survival (DSS) in patients who have testicular tumor. METHODS: The data of 67 patients who treated for primary testicular tumor at our clinic between January 2000 and December 2010 was evaluated retrospectively. Patients' age, histological type of tumor, pathologic stage, serum neutrophil and serum lymphocyte counts and NLR values were recorded. RESULTS: For all patients, mean age, mean serum neutrophil, lymphocyte counts and mean NLR were 33+-8, 4800+-2100, 1100+-520 and 3,69+-1.1, respectively. In histopathological examination, pure seminoma, pure non-seminom and mix histologic type were detected in 21(31.4%), 23(34.3%) and 23(34.3%) patients, respectively. Stage 1 disease and stage ≥2 disease were revealed in 42(62%) and 25(38%)of the patients. During median 67 months follow-up period, DSS rate was 91%. According to previous studies, we determined NLR cut-off value as 4. Patients were divided into two groups as NLR≤4 and NLR>4. There was no statistically significant difference on DSS between two groups. DISCUSSION AND CONCLUSION: According to our outcomes, we observed that NLR was not a prognostic factor to predict of DSS. However, high patient volume and prospective trials are needed to support our results. |
| first_indexed | 2024-03-09T07:12:06Z |
| format | Article |
| id | doaj.art-290b010ad1e84c86856d6ea49bec5430 |
| institution | Directory Open Access Journal |
| issn | 2587-0351 |
| language | English |
| last_indexed | 2024-03-09T07:12:06Z |
| publishDate | 2017-05-01 |
| publisher | Van Yuzuncu Yil University, School of Medicine |
| record_format | Article |
| series | Van Tıp Dergisi |
| spelling | doaj.art-290b010ad1e84c86856d6ea49bec54302023-12-03T09:01:10ZengVan Yuzuncu Yil University, School of MedicineVan Tıp Dergisi2587-03512017-05-0124210610910.5505/vtd.2017.75537VTD-75537The Effect of Preoperative Neutrophil-Lymphocyte Ratio on Disease Specific Survival in Testicular Tumor PatientsNurullah Hamidi0Evren Süer1Mehmet İlker Gökçe2Yaşar Bedük3Department of Urology, Ankara University, Ankara, TurkeyDepartment of Urology, Ankara University, Ankara, TurkeyDepartment of Urology, Ankara University, Ankara, TurkeyDepartment of Urology, Ankara University, Ankara, TurkeyINTRODUCTION: The effect of hemogram parameters on survival has been evaluated in many studies for patients who have urogenital tumor. In this study, we aimed to evaluate the neutrophil-lymphocyte ratio (NLR) on disease specific survival (DSS) in patients who have testicular tumor. METHODS: The data of 67 patients who treated for primary testicular tumor at our clinic between January 2000 and December 2010 was evaluated retrospectively. Patients' age, histological type of tumor, pathologic stage, serum neutrophil and serum lymphocyte counts and NLR values were recorded. RESULTS: For all patients, mean age, mean serum neutrophil, lymphocyte counts and mean NLR were 33+-8, 4800+-2100, 1100+-520 and 3,69+-1.1, respectively. In histopathological examination, pure seminoma, pure non-seminom and mix histologic type were detected in 21(31.4%), 23(34.3%) and 23(34.3%) patients, respectively. Stage 1 disease and stage ≥2 disease were revealed in 42(62%) and 25(38%)of the patients. During median 67 months follow-up period, DSS rate was 91%. According to previous studies, we determined NLR cut-off value as 4. Patients were divided into two groups as NLR≤4 and NLR>4. There was no statistically significant difference on DSS between two groups. DISCUSSION AND CONCLUSION: According to our outcomes, we observed that NLR was not a prognostic factor to predict of DSS. However, high patient volume and prospective trials are needed to support our results.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-75537neutrophil-lymphocyte ratiosurvivaltesticular tumor |
| spellingShingle | Nurullah Hamidi Evren Süer Mehmet İlker Gökçe Yaşar Bedük The Effect of Preoperative Neutrophil-Lymphocyte Ratio on Disease Specific Survival in Testicular Tumor Patients Van Tıp Dergisi neutrophil-lymphocyte ratio survival testicular tumor |
| title | The Effect of Preoperative Neutrophil-Lymphocyte Ratio on Disease Specific Survival in Testicular Tumor Patients |
| title_full | The Effect of Preoperative Neutrophil-Lymphocyte Ratio on Disease Specific Survival in Testicular Tumor Patients |
| title_fullStr | The Effect of Preoperative Neutrophil-Lymphocyte Ratio on Disease Specific Survival in Testicular Tumor Patients |
| title_full_unstemmed | The Effect of Preoperative Neutrophil-Lymphocyte Ratio on Disease Specific Survival in Testicular Tumor Patients |
| title_short | The Effect of Preoperative Neutrophil-Lymphocyte Ratio on Disease Specific Survival in Testicular Tumor Patients |
| title_sort | effect of preoperative neutrophil lymphocyte ratio on disease specific survival in testicular tumor patients |
| topic | neutrophil-lymphocyte ratio survival testicular tumor |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=vtd&un=VTD-75537 |
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