Aplasia cutis congenita in monozygotic twins
Abstract Aplasia cutis congenita (ACC) is defined as complete or partial loss or absence of skin at birth and it can occur on any part of the body, but most commonly on the scalp. Single offspring with ACC have been reported in most case reports, but cases in twins are rarely reported. Here, we repo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-10-01
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| Series: | Skin Health and Disease |
| Online Access: | https://doi.org/10.1002/ski2.270 |
| _version_ | 1827799818998644736 |
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| author | Hui‐Jun Lai Mei‐Yan Lai Ping‐Ping Ma Hong‐Wei Guo |
| author_facet | Hui‐Jun Lai Mei‐Yan Lai Ping‐Ping Ma Hong‐Wei Guo |
| author_sort | Hui‐Jun Lai |
| collection | DOAJ |
| description | Abstract Aplasia cutis congenita (ACC) is defined as complete or partial loss or absence of skin at birth and it can occur on any part of the body, but most commonly on the scalp. Single offspring with ACC have been reported in most case reports, but cases in twins are rarely reported. Here, we report two cases of ACC, monozygotic twin boys presented with scattered skin absence over the scalp vertex after birth. All the lesions presented as ulcers with no hair and healed with scars, otherwise, the twins were well developed mentally and physically. In addition, the whole exome sequencing of the twins and their parents might provide diagnosis and classification assistance. |
| first_indexed | 2024-03-11T19:57:12Z |
| format | Article |
| id | doaj.art-290c4e296839486d8469fa2e103d6508 |
| institution | Directory Open Access Journal |
| issn | 2690-442X |
| language | English |
| last_indexed | 2024-03-11T19:57:12Z |
| publishDate | 2023-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Skin Health and Disease |
| spelling | doaj.art-290c4e296839486d8469fa2e103d65082023-10-04T14:55:12ZengWileySkin Health and Disease2690-442X2023-10-0135n/an/a10.1002/ski2.270Aplasia cutis congenita in monozygotic twinsHui‐Jun Lai0Mei‐Yan Lai1Ping‐Ping Ma2Hong‐Wei Guo3The First Clinical Medical School Guangdong Medical University Zhanjiang Guangdong ChinaThe First Clinical Medical School Guangdong Medical University Zhanjiang Guangdong ChinaDepartment of Dermatology Affiliated Hospital of Guangdong Medical University Zhanjiang Guangdong ChinaThe First Clinical Medical School Guangdong Medical University Zhanjiang Guangdong ChinaAbstract Aplasia cutis congenita (ACC) is defined as complete or partial loss or absence of skin at birth and it can occur on any part of the body, but most commonly on the scalp. Single offspring with ACC have been reported in most case reports, but cases in twins are rarely reported. Here, we report two cases of ACC, monozygotic twin boys presented with scattered skin absence over the scalp vertex after birth. All the lesions presented as ulcers with no hair and healed with scars, otherwise, the twins were well developed mentally and physically. In addition, the whole exome sequencing of the twins and their parents might provide diagnosis and classification assistance.https://doi.org/10.1002/ski2.270 |
| spellingShingle | Hui‐Jun Lai Mei‐Yan Lai Ping‐Ping Ma Hong‐Wei Guo Aplasia cutis congenita in monozygotic twins Skin Health and Disease |
| title | Aplasia cutis congenita in monozygotic twins |
| title_full | Aplasia cutis congenita in monozygotic twins |
| title_fullStr | Aplasia cutis congenita in monozygotic twins |
| title_full_unstemmed | Aplasia cutis congenita in monozygotic twins |
| title_short | Aplasia cutis congenita in monozygotic twins |
| title_sort | aplasia cutis congenita in monozygotic twins |
| url | https://doi.org/10.1002/ski2.270 |
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