Boosting Microglial Lipid Metabolism via TREM2 Signaling by Biomimetic Nanoparticles to Attenuate the Sevoflurane‐Induced Developmental Neurotoxicity

Boosting Microglial Lipid Metabolism via TREM2 Signaling by Biomimetic Nanoparticles to Attenuate the Sevoflurane‐Induced Developmental Neurotoxicity

Abstract Lipid metabolism has been considered as a potential therapeutic target in sevoflurane‐induced neurotoxicity that can potentially affect the learning and memory function in the developmental brain. Recently, triggering receptor expressed on myeloid cells 2 (TREM2) is identified as a crucial...

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Bibliographic Details
Main Authors: Wenting Li, Xiaowen Meng, Ke Peng, Yaobao Han, Hanghang Liu, Weiming Zhao, Gang Wang, Li Deng, Hong Liu, Zhen Li, Fuhai Ji
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
biomimetic nanoparticles
lipid metabolism
neuroinflammation
sevoflurane‐induced neurotoxicity
TREM2
Online Access:https://doi.org/10.1002/advs.202305989

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