Relationship between the Thyroid Hormone and Viral Infections in Pregnancy
Pregnancy requires an important interpretation of thyroid function tests. The presence of anti-thyroid antibodies and viral infectious agents affect the health of both the fetus and the mother. Hence, a selective evaluation of thyroid function in pregnancy is required. This study is a retrospectiv...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Korean Society for Clinical Laboratory Science
2022-03-01
|
| Series: | Korean Journal of Clinical Laboratory Science |
| Subjects: |
| _version_ | 1818312908380045312 |
|---|---|
| author | Dong-Kyu Lim Chang-Eun Park |
| author_facet | Dong-Kyu Lim Chang-Eun Park |
| author_sort | Dong-Kyu Lim |
| collection | DOAJ |
| description | Pregnancy requires an important interpretation of thyroid function tests. The presence of anti-thyroid
antibodies and viral infectious agents affect the health of both the fetus and the mother. Hence, a
selective evaluation of thyroid function in pregnancy is required. This study is a retrospective
cross-sectional survey to examine the correlation between thyroid hormones and viral infections
during pregnancy. The results showed that the triiodothyronine (T3) decreased with increasing age,
especially in the hepatitis C virus (HCV)-positive group (P＜0.01). In addition, although negative for
the human immunodeficiency virus (HIV), thyroxine (FT4) showed a significant increase in
near-threshold or twin pregnant women (P＜0.05). The thyroid stimulating hormone (TSH) was
highly distributed at the age of 30, and there was no statistically significant correlation with other viral
infection factors. In addition, as a result of dividing and analyzing the result of TSH by the quantiles,
FT4 and T3 showed a positive correlation but showed a negative correlation with TSH (P ＜0.05).
Therefore, the evaluation of prenatal thyroid screening during pregnancy and viral infection factors
should reflect the time of pregnancy, exposure to infection, and the quantitative values. Adequate
thyroid hormone and viral infections availability is important for an uncomplicated pregnancy and
optimal fetal development. |
| first_indexed | 2024-12-13T08:25:19Z |
| format | Article |
| id | doaj.art-290cf27c72714d71b2d5817cbaa682d2 |
| institution | Directory Open Access Journal |
| issn | 1738-3544 2288-1662 |
| language | English |
| last_indexed | 2024-12-13T08:25:19Z |
| publishDate | 2022-03-01 |
| publisher | The Korean Society for Clinical Laboratory Science |
| record_format | Article |
| series | Korean Journal of Clinical Laboratory Science |
| spelling | doaj.art-290cf27c72714d71b2d5817cbaa682d22022-12-21T23:53:53ZengThe Korean Society for Clinical Laboratory ScienceKorean Journal of Clinical Laboratory Science1738-35442288-16622022-03-01541283710.15324/kjcls.2022.54.1.28Relationship between the Thyroid Hormone and Viral Infections in PregnancyDong-Kyu Lim0Chang-Eun Park1https://orcid.org/0000-0003-4259-7928Department of Laboratory Medicine, CHA Bundang Women's Medical Center, Seongnam, KoreaDepartment of Biomedical Laboratory Science, Molecular Diagnostics Research Institute, Namseoul University, Cheonan, KoreaPregnancy requires an important interpretation of thyroid function tests. The presence of anti-thyroid antibodies and viral infectious agents affect the health of both the fetus and the mother. Hence, a selective evaluation of thyroid function in pregnancy is required. This study is a retrospective cross-sectional survey to examine the correlation between thyroid hormones and viral infections during pregnancy. The results showed that the triiodothyronine (T3) decreased with increasing age, especially in the hepatitis C virus (HCV)-positive group (P＜0.01). In addition, although negative for the human immunodeficiency virus (HIV), thyroxine (FT4) showed a significant increase in near-threshold or twin pregnant women (P＜0.05). The thyroid stimulating hormone (TSH) was highly distributed at the age of 30, and there was no statistically significant correlation with other viral infection factors. In addition, as a result of dividing and analyzing the result of TSH by the quantiles, FT4 and T3 showed a positive correlation but showed a negative correlation with TSH (P ＜0.05). Therefore, the evaluation of prenatal thyroid screening during pregnancy and viral infection factors should reflect the time of pregnancy, exposure to infection, and the quantitative values. Adequate thyroid hormone and viral infections availability is important for an uncomplicated pregnancy and optimal fetal development.free t4pregnancythyroid stimulating hormonetriiodothyroninevirus infection |
| spellingShingle | Dong-Kyu Lim Chang-Eun Park Relationship between the Thyroid Hormone and Viral Infections in Pregnancy Korean Journal of Clinical Laboratory Science free t4 pregnancy thyroid stimulating hormone triiodothyronine virus infection |
| title | Relationship between the Thyroid Hormone and Viral Infections in Pregnancy |
| title_full | Relationship between the Thyroid Hormone and Viral Infections in Pregnancy |
| title_fullStr | Relationship between the Thyroid Hormone and Viral Infections in Pregnancy |
| title_full_unstemmed | Relationship between the Thyroid Hormone and Viral Infections in Pregnancy |
| title_short | Relationship between the Thyroid Hormone and Viral Infections in Pregnancy |
| title_sort | relationship between the thyroid hormone and viral infections in pregnancy |
| topic | free t4 pregnancy thyroid stimulating hormone triiodothyronine virus infection |
| work_keys_str_mv | AT dongkyulim relationshipbetweenthethyroidhormoneandviralinfectionsinpregnancy AT changeunpark relationshipbetweenthethyroidhormoneandviralinfectionsinpregnancy |