A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações
The Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as "click" reaction, has become a very popular reaction in the last years. It affords exclusively 1,4-disubstituted 1,2,3-triazoles and has been widely used to connect readily accessible building blocks containing v...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2011-01-01
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011001000012&lng=en&tlng=en |
| _version_ | 1811224640907902976 |
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| author | Luiza Baptista de Oliveira Freitas Fernando Armini Ruela Guilherme Rocha Pereira Rosemeire Brondi Alves Rossimiriam Pereira de Freitas Leandro José dos Santos |
| author_facet | Luiza Baptista de Oliveira Freitas Fernando Armini Ruela Guilherme Rocha Pereira Rosemeire Brondi Alves Rossimiriam Pereira de Freitas Leandro José dos Santos |
| author_sort | Luiza Baptista de Oliveira Freitas |
| collection | DOAJ |
| description | The Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as "click" reaction, has become a very popular reaction in the last years. It affords exclusively 1,4-disubstituted 1,2,3-triazoles and has been widely used to connect readily accessible building blocks containing various functional groups. The great success of this reaction is based on the fact that it is general, virtually quantitative and very robuste. The scope of this copper-catalyzed synthesis is extraordinary and the reaction has found numerous applications in many research fields, including biological chemistry and materials science. In this review, the main chemical aspects and applications of the "click" reaction in the synthesis of 1,2,3-triazoles are presented. |
| first_indexed | 2024-04-12T08:51:20Z |
| format | Article |
| id | doaj.art-290d011147bd44a88cf087961a082e9d |
| institution | Directory Open Access Journal |
| issn | 1678-7064 |
| language | English |
| last_indexed | 2024-04-12T08:51:20Z |
| publishDate | 2011-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-290d011147bd44a88cf087961a082e9d2022-12-22T03:39:33ZengSociedade Brasileira de QuímicaQuímica Nova1678-70642011-01-0134101791180410.1590/S0100-40422011001000012S0100-40422011001000012A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicaçõesLuiza Baptista de Oliveira Freitas0Fernando Armini Ruela1Guilherme Rocha Pereira2Rosemeire Brondi Alves3Rossimiriam Pereira de Freitas4Leandro José dos Santos5Universidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de Minas GeraisUniversidade Federal de ViçosaThe Copper-catalyzed azide-alkyne cycloaddition (CuAAC), often referred to as "click" reaction, has become a very popular reaction in the last years. It affords exclusively 1,4-disubstituted 1,2,3-triazoles and has been widely used to connect readily accessible building blocks containing various functional groups. The great success of this reaction is based on the fact that it is general, virtually quantitative and very robuste. The scope of this copper-catalyzed synthesis is extraordinary and the reaction has found numerous applications in many research fields, including biological chemistry and materials science. In this review, the main chemical aspects and applications of the "click" reaction in the synthesis of 1,2,3-triazoles are presented.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011001000012&lng=en&tlng=enclickreactioncycloadditiontriazole |
| spellingShingle | Luiza Baptista de Oliveira Freitas Fernando Armini Ruela Guilherme Rocha Pereira Rosemeire Brondi Alves Rossimiriam Pereira de Freitas Leandro José dos Santos A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações Química Nova click reaction cycloaddition triazole |
| title | A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações |
| title_full | A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações |
| title_fullStr | A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações |
| title_full_unstemmed | A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações |
| title_short | A reação "click" na síntese de 1,2,3-triazóis: aspectos químicos e aplicações |
| title_sort | reacao click na sintese de 1 2 3 triazois aspectos quimicos e aplicacoes |
| topic | click reaction cycloaddition triazole |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011001000012&lng=en&tlng=en |
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