Outcome and Causes of Acute Renal Failure in Women during Peripartum Period

OBJECTIVE: To find the causes of occurrence and outcome of acute renal failure in women during peripartum period. METHODOLOGY: This prospective study was conducted in department of Gynae & Obsts. in collaboration with urology department at Liaquat University of Medical & Health Sciences...

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Main Authors: Dr. Shazia Awan, Dr. Saira Dars, Dr. Saima Junejo, Dr. Shazia Rani, Dr. Raheel Sikandar
Format: Article
Language:English
Published: Liaquat University of Medical and Health Sciences 2020-03-01
Series:JLUMHS
Subjects:
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author Dr. Shazia Awan
Dr. Saira Dars
Dr. Saima Junejo
Dr. Shazia Rani
Dr. Raheel Sikandar
author_facet Dr. Shazia Awan
Dr. Saira Dars
Dr. Saima Junejo
Dr. Shazia Rani
Dr. Raheel Sikandar
author_sort Dr. Shazia Awan
collection DOAJ
description OBJECTIVE: To find the causes of occurrence and outcome of acute renal failure in women during peripartum period. METHODOLOGY: This prospective study was conducted in department of Gynae & Obsts. in collaboration with urology department at Liaquat University of Medical & Health Sciences Jamshoro from February 2015 to January 2017. Sample size was 90, overwhelming patients coming from peripheral area. Data was analyzed in SPSS version 21.0. Mean and standard deviation for quantitative variables such as age, gravidity & parity, frequency and percentages were calculated for qualitative variables; pre-eclampsia, eclampsia, hemolysis, post and antepartum hemorrhages, high liver enzymes, puerperal sepsis, low platelets, disseminated intravascular coagulation and outcomes like complete, partial and non-recovery. T-test was applied to evaluate the causes and outcomes. P value (P < 0.05) was considered as significant. RESULTS: Causes of 90 patients, which includes pre-eclampsia, eclampsia 11(12.22%), Postpartum hemorrhage 9(10%), Ante-partum hemorrhage 10(11.11%), 27 (30%) Hemorrhage, HELLP Syndrome 3(3.33%), purpeural sepsis and disseminated intravascular coagulation 7(7.77%), Ruptured Uterus 4(4.44%), hemolysis, elevated liver enzyme and Low Platelets Syndrome 5(5.55%), disseminated intravascular coagulation 4(4.44%), Dehydration 4(4.44%) and Obstructed Labor 6(6.66%). Outcome of acute renal failure in women during peripartum period, includes maternal outcome, delayed complete recovery, partial recovery, non-recovery, referred for dialysis. CONCLUSION: We concluded that the frequently causes were peripartum haemorrhage, eclampsia pre-eclampsia, puerperal sepsis and these sources were risk factors to increase morbidity and mortality.
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spelling doaj.art-290ee43e419744a49213da58861ae2062022-12-22T02:27:04ZengLiaquat University of Medical and Health SciencesJLUMHS1729-03412309-86272020-03-01191202310.22442/jlumhs.201910655Outcome and Causes of Acute Renal Failure in Women during Peripartum PeriodDr. Shazia Awan 0Dr. Saira Dars 1Dr. Saima Junejo 2Dr. Shazia Rani 3Dr. Raheel Sikandar 4Assistant Professor Department of Gynae/ Obs. Liaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Sindh-Pakistan.Senior Registrar Department of Gynae/ Obs. LUMHS, Jamshoro, Sindh-Pakistan.Postgraduate Student Department of Gynae/ Obs. LUMHS, Jamshoro, Sindh-Pakistan.Assistant Professor Department of Gynae/ Obs. LUMHS, Jamshoro, Sindh-Pakistan.Professor Department of Gynae/ Obs. LUMHS, Jamshoro, Sindh-Pakistan.OBJECTIVE: To find the causes of occurrence and outcome of acute renal failure in women during peripartum period. METHODOLOGY: This prospective study was conducted in department of Gynae & Obsts. in collaboration with urology department at Liaquat University of Medical & Health Sciences Jamshoro from February 2015 to January 2017. Sample size was 90, overwhelming patients coming from peripheral area. Data was analyzed in SPSS version 21.0. Mean and standard deviation for quantitative variables such as age, gravidity & parity, frequency and percentages were calculated for qualitative variables; pre-eclampsia, eclampsia, hemolysis, post and antepartum hemorrhages, high liver enzymes, puerperal sepsis, low platelets, disseminated intravascular coagulation and outcomes like complete, partial and non-recovery. T-test was applied to evaluate the causes and outcomes. P value (P < 0.05) was considered as significant. RESULTS: Causes of 90 patients, which includes pre-eclampsia, eclampsia 11(12.22%), Postpartum hemorrhage 9(10%), Ante-partum hemorrhage 10(11.11%), 27 (30%) Hemorrhage, HELLP Syndrome 3(3.33%), purpeural sepsis and disseminated intravascular coagulation 7(7.77%), Ruptured Uterus 4(4.44%), hemolysis, elevated liver enzyme and Low Platelets Syndrome 5(5.55%), disseminated intravascular coagulation 4(4.44%), Dehydration 4(4.44%) and Obstructed Labor 6(6.66%). Outcome of acute renal failure in women during peripartum period, includes maternal outcome, delayed complete recovery, partial recovery, non-recovery, referred for dialysis. CONCLUSION: We concluded that the frequently causes were peripartum haemorrhage, eclampsia pre-eclampsia, puerperal sepsis and these sources were risk factors to increase morbidity and mortality.acute renal failurewomenperipartum period.
spellingShingle Dr. Shazia Awan
Dr. Saira Dars
Dr. Saima Junejo
Dr. Shazia Rani
Dr. Raheel Sikandar
Outcome and Causes of Acute Renal Failure in Women during Peripartum Period
JLUMHS
acute renal failure
women
peripartum period.
title Outcome and Causes of Acute Renal Failure in Women during Peripartum Period
title_full Outcome and Causes of Acute Renal Failure in Women during Peripartum Period
title_fullStr Outcome and Causes of Acute Renal Failure in Women during Peripartum Period
title_full_unstemmed Outcome and Causes of Acute Renal Failure in Women during Peripartum Period
title_short Outcome and Causes of Acute Renal Failure in Women during Peripartum Period
title_sort outcome and causes of acute renal failure in women during peripartum period
topic acute renal failure
women
peripartum period.
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AT drsairadars outcomeandcausesofacuterenalfailureinwomenduringperipartumperiod
AT drsaimajunejo outcomeandcausesofacuterenalfailureinwomenduringperipartumperiod
AT drshaziarani outcomeandcausesofacuterenalfailureinwomenduringperipartumperiod
AT drraheelsikandar outcomeandcausesofacuterenalfailureinwomenduringperipartumperiod