The role of CMV in glioblastoma and implications for immunotherapeutic strategies

The role of CMV in glioblastoma and implications for immunotherapeutic strategies

Controversy surrounds the role of cytomegalovirus (CMV) in glioblastoma (GBM). However, several studies have shown that CMV nucleic acids and proteins are present within GBM tumor tissue. CMV has been implicated in GBM pathogenesis by affecting tumor stem cell factors, angiogenesis and immune pathwa...

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Bibliographic Details
Main Authors: Maryam Rahman, Farhad Dastmalchi, Aida Karachi, Duane Mitchell
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:OncoImmunology
Subjects:
glioblastoma
brain tumors
immunotherapy
dendritic cells
vaccines
cytomegalovirus
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1514921

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