Successful management of a kitten with chlorpyrifos and cypermethrin toxicosis with pralidoxime and atropine
Case summary Organophosphates and pyrethroids have been widely used as agricultural and domestic insecticides. This case report describes a 3-month-old free-roaming female kitten, weighing 930 g, that developed hypersalivation, hypothermia, dyspnoea due to increased bronchial secretion, bradycardia,...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2021-09-01
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| Series: | Journal of Feline Medicine and Surgery Open Reports |
| Online Access: | https://doi.org/10.1177/20551169211045647 |
| _version_ | 1818650509263765504 |
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| author | Sawrab Roy Saiful Islam Shahrul Alam Juned Ahmed Q M Monzur Kader Chowdhury |
| author_facet | Sawrab Roy Saiful Islam Shahrul Alam Juned Ahmed Q M Monzur Kader Chowdhury |
| author_sort | Sawrab Roy |
| collection | DOAJ |
| description | Case summary Organophosphates and pyrethroids have been widely used as agricultural and domestic insecticides. This case report describes a 3-month-old free-roaming female kitten, weighing 930 g, that developed hypersalivation, hypothermia, dyspnoea due to increased bronchial secretion, bradycardia, miosis and neurological signs, including restlessness, ataxia, disorientation, apparent hallucination, muscle twitching and seizures within 6 h of accidental ingestion of an insecticide containing chlorpyrifos (500 g/l) and cypermethrin (50 g/l). The kitten was treated empirically with intramuscular atropine and dexamethasone, and rectal diazepam. The history of insecticide exposure was obtained after 6 h of treatment and intramuscular 2-pyridine aldoxime methochloride (pralidoxime [2-PAM]) and atropine therapy was started 2 h later. Recovery was complicated by suspected aspiration, but there were no sequelae from the insecticide exposure and by 7 days post-ingestion the kitten was normal and playful. Relevance and novel information To the best of our knowledge, this is the first report of successful management of chlorpyrifos and cypermethrin toxicosis in a cat in Bangladesh. This case report suggests that 2-PAM followed by atropine and other supportive therapy may be an effective strategy to manage a cat poisoned by chlorpyrifos and cypermethrin; however, expanded clinical trials are needed. |
| first_indexed | 2024-12-17T01:51:21Z |
| format | Article |
| id | doaj.art-29121a0bdac24533aa20abab1272ee0a |
| institution | Directory Open Access Journal |
| issn | 2055-1169 |
| language | English |
| last_indexed | 2024-12-17T01:51:21Z |
| publishDate | 2021-09-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Feline Medicine and Surgery Open Reports |
| spelling | doaj.art-29121a0bdac24533aa20abab1272ee0a2022-12-21T22:08:03ZengSAGE PublishingJournal of Feline Medicine and Surgery Open Reports2055-11692021-09-01710.1177/20551169211045647Successful management of a kitten with chlorpyrifos and cypermethrin toxicosis with pralidoxime and atropineSawrab Roy0Saiful Islam1Shahrul Alam2Juned Ahmed3Q M Monzur Kader Chowdhury4Sylhet Pet Care, Sylhet, BangladeshDepartment of Livestock Production and Management, Sylhet Agricultural University, Sylhet, BangladeshFaculty of Agricultural and Nutritional Sciences, Christian Albrechts University of Kiel, GermanyDepartment of Pathology, Sylhet Agricultural University, Sylhet, BangladeshDepartment of Comparative Biomedical Sciences, College of Veterinary Medicine, Mississippi State University, MS, USACase summary Organophosphates and pyrethroids have been widely used as agricultural and domestic insecticides. This case report describes a 3-month-old free-roaming female kitten, weighing 930 g, that developed hypersalivation, hypothermia, dyspnoea due to increased bronchial secretion, bradycardia, miosis and neurological signs, including restlessness, ataxia, disorientation, apparent hallucination, muscle twitching and seizures within 6 h of accidental ingestion of an insecticide containing chlorpyrifos (500 g/l) and cypermethrin (50 g/l). The kitten was treated empirically with intramuscular atropine and dexamethasone, and rectal diazepam. The history of insecticide exposure was obtained after 6 h of treatment and intramuscular 2-pyridine aldoxime methochloride (pralidoxime [2-PAM]) and atropine therapy was started 2 h later. Recovery was complicated by suspected aspiration, but there were no sequelae from the insecticide exposure and by 7 days post-ingestion the kitten was normal and playful. Relevance and novel information To the best of our knowledge, this is the first report of successful management of chlorpyrifos and cypermethrin toxicosis in a cat in Bangladesh. This case report suggests that 2-PAM followed by atropine and other supportive therapy may be an effective strategy to manage a cat poisoned by chlorpyrifos and cypermethrin; however, expanded clinical trials are needed.https://doi.org/10.1177/20551169211045647 |
| spellingShingle | Sawrab Roy Saiful Islam Shahrul Alam Juned Ahmed Q M Monzur Kader Chowdhury Successful management of a kitten with chlorpyrifos and cypermethrin toxicosis with pralidoxime and atropine Journal of Feline Medicine and Surgery Open Reports |
| title | Successful management of a kitten with chlorpyrifos and cypermethrin toxicosis with pralidoxime and atropine |
| title_full | Successful management of a kitten with chlorpyrifos and cypermethrin toxicosis with pralidoxime and atropine |
| title_fullStr | Successful management of a kitten with chlorpyrifos and cypermethrin toxicosis with pralidoxime and atropine |
| title_full_unstemmed | Successful management of a kitten with chlorpyrifos and cypermethrin toxicosis with pralidoxime and atropine |
| title_short | Successful management of a kitten with chlorpyrifos and cypermethrin toxicosis with pralidoxime and atropine |
| title_sort | successful management of a kitten with chlorpyrifos and cypermethrin toxicosis with pralidoxime and atropine |
| url | https://doi.org/10.1177/20551169211045647 |
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