Improvement in Muscular Strength in HIV-Infected Individuals Receiving Antiretroviral Therapy
Purpose: This study investigated (1) the effect of a progressive resistance training (PRT) program and whey protein intake on maximal muscle strength in human immunodeficiency virus (HIV)-infected individuals receiving antiretroviral therapy (ART) and (2) alterations in maximal strength 12 wks after...
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-09-01
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| Series: | Journal of Functional Morphology and Kinesiology |
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| Online Access: | https://www.mdpi.com/2411-5142/4/3/66 |
| _version_ | 1819148953167331328 |
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| author | Takshita Sookan Ayesha Motala Michael Ormsbee Jose Antonio Nombulelo Magula Umesh Lalloo Andrew McKune |
| author_facet | Takshita Sookan Ayesha Motala Michael Ormsbee Jose Antonio Nombulelo Magula Umesh Lalloo Andrew McKune |
| author_sort | Takshita Sookan |
| collection | DOAJ |
| description | Purpose: This study investigated (1) the effect of a progressive resistance training (PRT) program and whey protein intake on maximal muscle strength in human immunodeficiency virus (HIV)-infected individuals receiving antiretroviral therapy (ART) and (2) alterations in maximal strength 12 wks after the cessation of PRT with continued supplementation. Methods: Sixty HIV-infected individuals were recruited. Whole body PRT was performed twice weekly for 12 wks. Participants received, in a double-blind placebo controlled manner, either 20 g whey or placebo (maltodextrin) before and immediately after each session. Both PRT groups continued to take either whey protein or placebo for a further 12 wks following the exercise intervention to examine the effects of detraining. Results: Forty participants (mean and standard deviation (SD) age 40.8 (±7.7) years, weight 70.8 (±16) kg, body mass index (BMI) 30.9 (±7.2) kg m<sup>2</sup>); whey protein /PRT (<i>n</i> = 13), placebo/PRT (<i>n</i> = 17), and a control group (<i>n</i> = 10) completed the study. A significant main effect for time occurred for the bench press (<i>p</i> = 0.02), the squat (<i>p</i> < 0.0001), the deadlift (<i>p</i> = 0.001) and the shoulder press (<i>p</i> = 0.02) one-repetition maximum (1RM) in the intervention groups. Conclusion: The PRT program increased maximal strength regardless of whey protein intake. The detraining period demonstrated minimal strength loss, which is beneficial to this population. |
| first_indexed | 2024-12-22T13:53:54Z |
| format | Article |
| id | doaj.art-291643ad354e47b3addd1c14d9829a14 |
| institution | Directory Open Access Journal |
| issn | 2411-5142 |
| language | English |
| last_indexed | 2024-12-22T13:53:54Z |
| publishDate | 2019-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Morphology and Kinesiology |
| spelling | doaj.art-291643ad354e47b3addd1c14d9829a142022-12-21T18:23:36ZengMDPI AGJournal of Functional Morphology and Kinesiology2411-51422019-09-014366010.3390/jfmk4030066jfmk4030066Improvement in Muscular Strength in HIV-Infected Individuals Receiving Antiretroviral TherapyTakshita Sookan0Ayesha Motala1Michael Ormsbee2Jose Antonio3Nombulelo Magula4Umesh Lalloo5Andrew McKune6Biokinetics, Exercise and Leisure Sciences, University of KwaZulu-Natal College of Health Sciences, Durban 4000, KwaZulu Natal, South AfricaDepartment of Diabetes and Endocrinology, University of KwaZulu-Natal College of Health Sciences, Durban 4013, KwaZulu Natal, South AfricaBiokinetics, Exercise and Leisure Sciences, University of KwaZulu-Natal College of Health Sciences, Durban 4000, KwaZulu Natal, South AfricaExercise and Sport Science, Nova Southeastern University, Davie FL 33328, USADepartment of Internal Medicine Durban, University of KwaZulu-Natal College of Health Sciences, Durban 4013, KwaZulu Natal, South AfricaDepartment of Pulmonology Durban, University of KwaZulu-Natal College of Health Sciences, Durban 4013, KwaZulu Natal, South AfricaBiokinetics, Exercise and Leisure Sciences, University of KwaZulu-Natal College of Health Sciences, Durban 4000, KwaZulu Natal, South AfricaPurpose: This study investigated (1) the effect of a progressive resistance training (PRT) program and whey protein intake on maximal muscle strength in human immunodeficiency virus (HIV)-infected individuals receiving antiretroviral therapy (ART) and (2) alterations in maximal strength 12 wks after the cessation of PRT with continued supplementation. Methods: Sixty HIV-infected individuals were recruited. Whole body PRT was performed twice weekly for 12 wks. Participants received, in a double-blind placebo controlled manner, either 20 g whey or placebo (maltodextrin) before and immediately after each session. Both PRT groups continued to take either whey protein or placebo for a further 12 wks following the exercise intervention to examine the effects of detraining. Results: Forty participants (mean and standard deviation (SD) age 40.8 (±7.7) years, weight 70.8 (±16) kg, body mass index (BMI) 30.9 (±7.2) kg m<sup>2</sup>); whey protein /PRT (<i>n</i> = 13), placebo/PRT (<i>n</i> = 17), and a control group (<i>n</i> = 10) completed the study. A significant main effect for time occurred for the bench press (<i>p</i> = 0.02), the squat (<i>p</i> < 0.0001), the deadlift (<i>p</i> = 0.001) and the shoulder press (<i>p</i> = 0.02) one-repetition maximum (1RM) in the intervention groups. Conclusion: The PRT program increased maximal strength regardless of whey protein intake. The detraining period demonstrated minimal strength loss, which is beneficial to this population.https://www.mdpi.com/2411-5142/4/3/66resistance trainingwheyplacebodetrainingHIVexerciseART |
| spellingShingle | Takshita Sookan Ayesha Motala Michael Ormsbee Jose Antonio Nombulelo Magula Umesh Lalloo Andrew McKune Improvement in Muscular Strength in HIV-Infected Individuals Receiving Antiretroviral Therapy Journal of Functional Morphology and Kinesiology resistance training whey placebo detraining HIV exercise ART |
| title | Improvement in Muscular Strength in HIV-Infected Individuals Receiving Antiretroviral Therapy |
| title_full | Improvement in Muscular Strength in HIV-Infected Individuals Receiving Antiretroviral Therapy |
| title_fullStr | Improvement in Muscular Strength in HIV-Infected Individuals Receiving Antiretroviral Therapy |
| title_full_unstemmed | Improvement in Muscular Strength in HIV-Infected Individuals Receiving Antiretroviral Therapy |
| title_short | Improvement in Muscular Strength in HIV-Infected Individuals Receiving Antiretroviral Therapy |
| title_sort | improvement in muscular strength in hiv infected individuals receiving antiretroviral therapy |
| topic | resistance training whey placebo detraining HIV exercise ART |
| url | https://www.mdpi.com/2411-5142/4/3/66 |
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