Combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer – A case report
Endometrial cancer, also known as uterine cancer, is the second most common cancer affecting women globally and the fourth most prevalent in the United States (US). Treatment often involves a combination of surgery, radiotherapy and chemotherapy depending on the severity. In this case report, we pre...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Gynecologic Oncology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352578922001709 |
| _version_ | 1811292039512326144 |
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| author | Luiza Chepkemoi Oluwaseyi Ajayi Nancy Anabaraonye Onyinye D. Balogun |
| author_facet | Luiza Chepkemoi Oluwaseyi Ajayi Nancy Anabaraonye Onyinye D. Balogun |
| author_sort | Luiza Chepkemoi |
| collection | DOAJ |
| description | Endometrial cancer, also known as uterine cancer, is the second most common cancer affecting women globally and the fourth most prevalent in the United States (US). Treatment often involves a combination of surgery, radiotherapy and chemotherapy depending on the severity. In this case report, we present two patients with relapsed endometrial carcinomas, who responded positively to combined radiotherapy and immunotherapy followed by maintenance immunotherapy.Given the worsening prognoses associated with recurrent endometrial cancers, these two cases warrant the further exploration of the concurrent administration of immunotherapy and radiation therapy in the context of clinical trials. |
| first_indexed | 2024-04-13T04:39:16Z |
| format | Article |
| id | doaj.art-2919251261614925bb69b7e01132f05b |
| institution | Directory Open Access Journal |
| issn | 2352-5789 |
| language | English |
| last_indexed | 2024-04-13T04:39:16Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Gynecologic Oncology Reports |
| spelling | doaj.art-2919251261614925bb69b7e01132f05b2022-12-22T03:02:04ZengElsevierGynecologic Oncology Reports2352-57892022-12-0144101090Combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer – A case reportLuiza Chepkemoi0Oluwaseyi Ajayi1Nancy Anabaraonye2Onyinye D. Balogun3Frank H. Netter MD School of Medicine at Quinnipiac University, North Haven, CT 06473, United StatesUniversity of Maryland, College Park, MD 20742, United StatesUniversity of Pennsylvania, Philadelphia, PA 19104, United StatesWeill Cornell Medicine/New York Presbyterian Hospital, New York, NY 10065, United States; Corresponding author at: Department of Radiation Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, 525 East 68th Street, Stich Radiation Center, New York, NY 10065, United States.Endometrial cancer, also known as uterine cancer, is the second most common cancer affecting women globally and the fourth most prevalent in the United States (US). Treatment often involves a combination of surgery, radiotherapy and chemotherapy depending on the severity. In this case report, we present two patients with relapsed endometrial carcinomas, who responded positively to combined radiotherapy and immunotherapy followed by maintenance immunotherapy.Given the worsening prognoses associated with recurrent endometrial cancers, these two cases warrant the further exploration of the concurrent administration of immunotherapy and radiation therapy in the context of clinical trials.http://www.sciencedirect.com/science/article/pii/S2352578922001709Case reportEndometrial cancerRadiotherapyImmunotherapyConcurrent radiotherapy and immunotherapy |
| spellingShingle | Luiza Chepkemoi Oluwaseyi Ajayi Nancy Anabaraonye Onyinye D. Balogun Combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer – A case report Gynecologic Oncology Reports Case report Endometrial cancer Radiotherapy Immunotherapy Concurrent radiotherapy and immunotherapy |
| title | Combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer – A case report |
| title_full | Combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer – A case report |
| title_fullStr | Combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer – A case report |
| title_full_unstemmed | Combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer – A case report |
| title_short | Combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer – A case report |
| title_sort | combining concurrent radiotherapy and immunotherapy for synergistic effects in recurrent endometrial cancer a case report |
| topic | Case report Endometrial cancer Radiotherapy Immunotherapy Concurrent radiotherapy and immunotherapy |
| url | http://www.sciencedirect.com/science/article/pii/S2352578922001709 |
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