Context-driven changes in l-DOPA-induced behaviours in the 6-OHDA lesioned rat

Context-driven changes in l-DOPA-induced behaviours in the 6-OHDA lesioned rat

Both contralateral rotational behaviour and dyskinetic abnormal involuntary movements (AIMs) are induced by the administration of l-DOPA in the unilateral 6-OHDA lesioned rat model of Parkinson's disease. Since rotational responses can be conditioned to environmental cues we have investigated t...

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Bibliographic Details
Main Authors: E.L. Lane, C.S. Daly, G.A. Smith, S.B. Dunnett
Format: Article
Language:English
Published: Elsevier 2011-04-01
Series:Neurobiology of Disease
Subjects:
Context-dependent conditioning
Context-specific sensitisation
l-DOPA-induced dyskinesia
Abnormal involuntary movements
Rotation
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111000118

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