Activation of Calcium-Activated Chloride Channels Suppresses Inherited Seizure Susceptibility in Genetically Epilepsy-Prone Rats

Activation of Calcium-Activated Chloride Channels Suppresses Inherited Seizure Susceptibility in Genetically Epilepsy-Prone Rats

Inherited seizure susceptibility in genetically epilepsy-prone rats (GEPR-3s) is associated with increased voltage-gated calcium channel currents suggesting a massive calcium influx resulting in increased levels of intraneuronal calcium. Cytosolic calcium, in turn, activates many processes, includin...

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Bibliographic Details
Main Authors:	Miracle Thomas, Mark Simms, Prosper N’Gouemo
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Biomedicines
Subjects:	acoustically evoked seizures EACT generalized tonic-clonic seizures inherited epilepsy TMEM1A channels wild running seizures
Online Access:	https://www.mdpi.com/2227-9059/10/2/449

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