Testicular histopathological diagnosis as a predictive factor for retrieving spermatozoa for ICSI in non-obstructive azoospermic patients
OBJECTIVE: Histological testicular pattern has a predictive role in the possibility of finding spermatozoa for ICSI in cases of non-obstructive azoospermia because some individuals could show residual spermatogenic sites in the testis. The aim of this study was to evaluate the sperm retrieval rate i...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Urologia
2005-08-01
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| Series: | International Brazilian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382005000400007 |
| _version_ | 1818838637668728832 |
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| author | Sidney Glina Jonathas B. Soares Nelson Antunes Jr Andrea G. Galuppo Lucero B. Paz Roberta Wonchockier |
| author_facet | Sidney Glina Jonathas B. Soares Nelson Antunes Jr Andrea G. Galuppo Lucero B. Paz Roberta Wonchockier |
| author_sort | Sidney Glina |
| collection | DOAJ |
| description | OBJECTIVE: Histological testicular pattern has a predictive role in the possibility of finding spermatozoa for ICSI in cases of non-obstructive azoospermia because some individuals could show residual spermatogenic sites in the testis. The aim of this study was to evaluate the sperm retrieval rate in each of the histopathological groups (hypospermatogenesis-Hypo, spermatogenic maturation arrest-MA, Sertoli cell only-SCO and testicular hyalinization) in patients assisted in our clinic. MATERIALS AND METHODS: Retrospective study from March 1997 to October 2002. We analyzed 14 patients with mean age of 34.3 ± 0.7, with non-obstructive azoospermia. All patients were submitted to previous diagnostic biopsy (Bx) elsewhere and came to our institution for treatment. After an average of 12 months (8 - 20), they were submitted to a new Bx procedure to retrieve sperm. RESULTS: Previous diagnostic Bx showed the following histopathological results: 5 patients with MA, 4 with Hypo and 5 SCO. In the following Bx (for sperm retrieval) spermatozoa was found in 33% of the procedures in patients with MA, 50% in patients with Hypo and 40% of the procedures in patients with SCO. CONCLUSION: Previous diagnostic Bx can help in patient counseling concerning the result of sperm retrieval. |
| first_indexed | 2024-12-19T03:41:34Z |
| format | Article |
| id | doaj.art-292ad98a87724930a3d3a7f43814663b |
| institution | Directory Open Access Journal |
| issn | 1677-5538 1677-6119 |
| language | English |
| last_indexed | 2024-12-19T03:41:34Z |
| publishDate | 2005-08-01 |
| publisher | Sociedade Brasileira de Urologia |
| record_format | Article |
| series | International Brazilian Journal of Urology |
| spelling | doaj.art-292ad98a87724930a3d3a7f43814663b2022-12-21T20:37:13ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-55381677-61192005-08-0131433834110.1590/S1677-55382005000400007Testicular histopathological diagnosis as a predictive factor for retrieving spermatozoa for ICSI in non-obstructive azoospermic patientsSidney GlinaJonathas B. SoaresNelson Antunes JrAndrea G. GaluppoLucero B. PazRoberta WonchockierOBJECTIVE: Histological testicular pattern has a predictive role in the possibility of finding spermatozoa for ICSI in cases of non-obstructive azoospermia because some individuals could show residual spermatogenic sites in the testis. The aim of this study was to evaluate the sperm retrieval rate in each of the histopathological groups (hypospermatogenesis-Hypo, spermatogenic maturation arrest-MA, Sertoli cell only-SCO and testicular hyalinization) in patients assisted in our clinic. MATERIALS AND METHODS: Retrospective study from March 1997 to October 2002. We analyzed 14 patients with mean age of 34.3 ± 0.7, with non-obstructive azoospermia. All patients were submitted to previous diagnostic biopsy (Bx) elsewhere and came to our institution for treatment. After an average of 12 months (8 - 20), they were submitted to a new Bx procedure to retrieve sperm. RESULTS: Previous diagnostic Bx showed the following histopathological results: 5 patients with MA, 4 with Hypo and 5 SCO. In the following Bx (for sperm retrieval) spermatozoa was found in 33% of the procedures in patients with MA, 50% in patients with Hypo and 40% of the procedures in patients with SCO. CONCLUSION: Previous diagnostic Bx can help in patient counseling concerning the result of sperm retrieval.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382005000400007azoospermiatestisbiopsyhistopathologysperm injectionsintracytoplasmic |
| spellingShingle | Sidney Glina Jonathas B. Soares Nelson Antunes Jr Andrea G. Galuppo Lucero B. Paz Roberta Wonchockier Testicular histopathological diagnosis as a predictive factor for retrieving spermatozoa for ICSI in non-obstructive azoospermic patients International Brazilian Journal of Urology azoospermia testis biopsy histopathology sperm injections intracytoplasmic |
| title | Testicular histopathological diagnosis as a predictive factor for retrieving spermatozoa for ICSI in non-obstructive azoospermic patients |
| title_full | Testicular histopathological diagnosis as a predictive factor for retrieving spermatozoa for ICSI in non-obstructive azoospermic patients |
| title_fullStr | Testicular histopathological diagnosis as a predictive factor for retrieving spermatozoa for ICSI in non-obstructive azoospermic patients |
| title_full_unstemmed | Testicular histopathological diagnosis as a predictive factor for retrieving spermatozoa for ICSI in non-obstructive azoospermic patients |
| title_short | Testicular histopathological diagnosis as a predictive factor for retrieving spermatozoa for ICSI in non-obstructive azoospermic patients |
| title_sort | testicular histopathological diagnosis as a predictive factor for retrieving spermatozoa for icsi in non obstructive azoospermic patients |
| topic | azoospermia testis biopsy histopathology sperm injections intracytoplasmic |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382005000400007 |
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