Nitrosopersulfide (SSNO−) accounts for sustained NO bioactivity of S-nitrosothiols following reaction with sulfide

Nitrosopersulfide (SSNO−) accounts for sustained NO bioactivity of S-nitrosothiols following reaction with sulfide

Sulfide salts are known to promote the release of nitric oxide (NO) from S-nitrosothiols and potentiate their vasorelaxant activity, but much of the cross-talk between hydrogen sulfide and NO is believed to occur via functional interactions of cell regulatory elements such as phosphodiesterases. Usi...

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Bibliographic Details
Main Authors: Miriam M. Cortese-Krott, Bernadette O. Fernandez, José L.T. Santos, Evanthia Mergia, Marian Grman, Péter Nagy, Malte Kelm, Anthony Butler, Martin Feelisch
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
Hydrogen sulfide
Nitric oxide
Polysulfides
cGMP
HSNO
Nitroxyl
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714000160

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http://www.sciencedirect.com/science/article/pii/S2213231714000160

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