Endoscopic features of colorectal lymphoma according to histological type
Abstract Background and Aim This study aimed to investigate the relationship between the histological type of colorectal lymphoma and its endoscopic features. Methods We retrospectively analyzed patients with primary colorectal lymphoma who were diagnosed using colonoscopy and biopsy specimens at th...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-04-01
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| Series: | JGH Open |
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| Online Access: | https://doi.org/10.1002/jgh3.12738 |
| _version_ | 1811304156004089856 |
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| author | Tatsuo Yachida Takahisa Matsuda Taku Sakamoto Takeshi Nakajima Yasuo Kakugawa Akiko Miyagi Maeshima Hirokazu Taniguchi Ryoji Kushima Kensei Tobinai Hideki Kobara Hisashi Masugata Tsutomu Masaki Yutaka Saito |
| author_facet | Tatsuo Yachida Takahisa Matsuda Taku Sakamoto Takeshi Nakajima Yasuo Kakugawa Akiko Miyagi Maeshima Hirokazu Taniguchi Ryoji Kushima Kensei Tobinai Hideki Kobara Hisashi Masugata Tsutomu Masaki Yutaka Saito |
| author_sort | Tatsuo Yachida |
| collection | DOAJ |
| description | Abstract Background and Aim This study aimed to investigate the relationship between the histological type of colorectal lymphoma and its endoscopic features. Methods We retrospectively analyzed patients with primary colorectal lymphoma who were diagnosed using colonoscopy and biopsy specimens at the National Cancer Center Hospital, Tokyo, Japan. The lesions were macroscopically classified into the following types via colonoscopy: polypoid, ulcerative, multiple lymphomatous polyposis, diffuse, and mixed. Results A total of 117 lesions were identified in 90 patients enrolled in this study. Of these, 59 (50%) were located in the ileocecal region, 23 (20%) in the rectum, 9 (8%) in the transverse colon, 8 (7%) in the sigmoid colon, 7 (6%) in the descending colon, and 4 (3%) in the ascending colon. Moreover, the most common histological subtypes were diffuse large B‐cell lymphoma (DLBCL) in 39 patients (43%) and mantle cell lymphoma (MCL) in 23 patients (26%), followed by follicular lymphoma (FL; 17%), mucosa‐associated lymphoid tissue (MALT) lymphoma (9%), peripheral T‐cell lymphoma‐NOS (2%), monomorphic epitheliotropic intestinal T‐cell lymphoma (MEITL; 2%), and Burkitt lymphoma (1%). More than half of the DLBCL (52%), MCL (52%), and MALT (56%) lymphomas were macroscopically classified as polypoid types. In contrast, FL lesions showed various macroscopic types. The majority of DLBCL (62%) and FL (78%) lesions were distributed in the ileocecal region. MCL lesions tended to be widely spread in various sites of the large intestine. Conclusions Colorectal lymphomas showed macroscopically distinctive features depending on the histological type. Understanding the macroscopic classification of the lesions by colonoscopy and its distribution may be helpful in diagnosing the type of lymphoma and determining the malignant grade based on the histological types. |
| first_indexed | 2024-04-13T08:01:10Z |
| format | Article |
| id | doaj.art-292fd20c6ede4fa89842e44b467127cd |
| institution | Directory Open Access Journal |
| issn | 2397-9070 |
| language | English |
| last_indexed | 2024-04-13T08:01:10Z |
| publishDate | 2022-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | JGH Open |
| spelling | doaj.art-292fd20c6ede4fa89842e44b467127cd2022-12-22T02:55:16ZengWileyJGH Open2397-90702022-04-016425726210.1002/jgh3.12738Endoscopic features of colorectal lymphoma according to histological typeTatsuo Yachida0Takahisa Matsuda1Taku Sakamoto2Takeshi Nakajima3Yasuo Kakugawa4Akiko Miyagi Maeshima5Hirokazu Taniguchi6Ryoji Kushima7Kensei Tobinai8Hideki Kobara9Hisashi Masugata10Tsutomu Masaki11Yutaka Saito12Endoscopy Division National Cancer Center Hospital Chuo City Tokyo JapanEndoscopy Division National Cancer Center Hospital Chuo City Tokyo JapanEndoscopy Division National Cancer Center Hospital Chuo City Tokyo JapanEndoscopy Division National Cancer Center Hospital Chuo City Tokyo JapanEndoscopy Division National Cancer Center Hospital Chuo City Tokyo JapanDepartment of Pathology National Cancer Center Hospital Chuo City Tokyo JapanDepartment of Pathology National Cancer Center Hospital Chuo City Tokyo JapanDepartment of Pathology National Cancer Center Hospital Chuo City Tokyo JapanDepartment of Hematology National Cancer Center Hospital Chuo City Tokyo JapanDepartment of Gastroenterology and Neurology, Faculty of Medicine Kagawa University Kita‐gun Kagawa JapanDepartment of General Internal Medicine, Faculty of Medicine Kagawa University Kita‐gun Kagawa JapanDepartment of Gastroenterology and Neurology, Faculty of Medicine Kagawa University Kita‐gun Kagawa JapanEndoscopy Division National Cancer Center Hospital Chuo City Tokyo JapanAbstract Background and Aim This study aimed to investigate the relationship between the histological type of colorectal lymphoma and its endoscopic features. Methods We retrospectively analyzed patients with primary colorectal lymphoma who were diagnosed using colonoscopy and biopsy specimens at the National Cancer Center Hospital, Tokyo, Japan. The lesions were macroscopically classified into the following types via colonoscopy: polypoid, ulcerative, multiple lymphomatous polyposis, diffuse, and mixed. Results A total of 117 lesions were identified in 90 patients enrolled in this study. Of these, 59 (50%) were located in the ileocecal region, 23 (20%) in the rectum, 9 (8%) in the transverse colon, 8 (7%) in the sigmoid colon, 7 (6%) in the descending colon, and 4 (3%) in the ascending colon. Moreover, the most common histological subtypes were diffuse large B‐cell lymphoma (DLBCL) in 39 patients (43%) and mantle cell lymphoma (MCL) in 23 patients (26%), followed by follicular lymphoma (FL; 17%), mucosa‐associated lymphoid tissue (MALT) lymphoma (9%), peripheral T‐cell lymphoma‐NOS (2%), monomorphic epitheliotropic intestinal T‐cell lymphoma (MEITL; 2%), and Burkitt lymphoma (1%). More than half of the DLBCL (52%), MCL (52%), and MALT (56%) lymphomas were macroscopically classified as polypoid types. In contrast, FL lesions showed various macroscopic types. The majority of DLBCL (62%) and FL (78%) lesions were distributed in the ileocecal region. MCL lesions tended to be widely spread in various sites of the large intestine. Conclusions Colorectal lymphomas showed macroscopically distinctive features depending on the histological type. Understanding the macroscopic classification of the lesions by colonoscopy and its distribution may be helpful in diagnosing the type of lymphoma and determining the malignant grade based on the histological types.https://doi.org/10.1002/jgh3.12738coloncolonoscopylymphoma |
| spellingShingle | Tatsuo Yachida Takahisa Matsuda Taku Sakamoto Takeshi Nakajima Yasuo Kakugawa Akiko Miyagi Maeshima Hirokazu Taniguchi Ryoji Kushima Kensei Tobinai Hideki Kobara Hisashi Masugata Tsutomu Masaki Yutaka Saito Endoscopic features of colorectal lymphoma according to histological type JGH Open colon colonoscopy lymphoma |
| title | Endoscopic features of colorectal lymphoma according to histological type |
| title_full | Endoscopic features of colorectal lymphoma according to histological type |
| title_fullStr | Endoscopic features of colorectal lymphoma according to histological type |
| title_full_unstemmed | Endoscopic features of colorectal lymphoma according to histological type |
| title_short | Endoscopic features of colorectal lymphoma according to histological type |
| title_sort | endoscopic features of colorectal lymphoma according to histological type |
| topic | colon colonoscopy lymphoma |
| url | https://doi.org/10.1002/jgh3.12738 |
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