National Physician Survey for Nonvalvular Atrial Fibrillation (NVAF) Anticoagulation Comparing Knowledge, Attitudes and Practice of Cardiologist to PCPs

Introduction: NVAF is estimated to affect between 6.4 and 7.4 million Americans in 2018, and increases the risk of stroke 5-fold. To mitigate this risk, guidelines recommend anticoagulating AF patients unless their stroke risk is very low. Despite these recommendations, 30.0-60.0% of NVAF patients d...

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Main Authors: Haseeb Saeed MD, Oscar Garza Ovalle MD, Ujala Bokhary MBBS, Anastasia Jermihov BS, Kamila Lepkowska MHA, Victoria Bauer BS, Kristine Kuchta MS, Marcia Wright PharmD, Scott Glosner BS, PharmD, BCPS, MPH, Margaret Frazer MD, Andres Quintero MD, MPH, MBA, Patrick Hlavacek MPH, Jack Mardekian PhD, Alfonso Tafur MD, Mark Metzl MD, Jorge Saucedo MD
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/1076029620952550
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author Haseeb Saeed MD
Oscar Garza Ovalle MD
Ujala Bokhary MBBS
Anastasia Jermihov BS
Kamila Lepkowska MHA
Victoria Bauer BS
Kristine Kuchta MS
Marcia Wright PharmD
Scott Glosner BS, PharmD, BCPS, MPH
Margaret Frazer MD
Andres Quintero MD, MPH, MBA
Patrick Hlavacek MPH
Jack Mardekian PhD
Alfonso Tafur MD
Mark Metzl MD
Jorge Saucedo MD
author_facet Haseeb Saeed MD
Oscar Garza Ovalle MD
Ujala Bokhary MBBS
Anastasia Jermihov BS
Kamila Lepkowska MHA
Victoria Bauer BS
Kristine Kuchta MS
Marcia Wright PharmD
Scott Glosner BS, PharmD, BCPS, MPH
Margaret Frazer MD
Andres Quintero MD, MPH, MBA
Patrick Hlavacek MPH
Jack Mardekian PhD
Alfonso Tafur MD
Mark Metzl MD
Jorge Saucedo MD
author_sort Haseeb Saeed MD
collection DOAJ
description Introduction: NVAF is estimated to affect between 6.4 and 7.4 million Americans in 2018, and increases the risk of stroke 5-fold. To mitigate this risk, guidelines recommend anticoagulating AF patients unless their stroke risk is very low. Despite these recommendations, 30.0-60.0% of NVAF patients do not receive indicated anticoagulation. To better understand why this may be, we surveyed PCPs and cardiologists nationwide on their attitudes, knowledge and practices toward managing NVAF with warfarin and direct-acting oral anticoagulants (DOACs). Methods: We surveyed 1,000 PCPs and 500 cardiologists selected randomly from a master list of the American Medical Association, using a paper based, anonymous, self-administered, mailed scannable survey. The survey contained questions on key demographics and data concerning attitudes, knowledge and practices related to prescribing DOACs. The surveys went out in the fall/winter of 2017-8 with a $10 incentive gift card. Survey responses were scanned into an Excel database and analyzed using SAS 9.3 (Cary, NC) for descriptive and inferential statistics. Results: Two hundred and forty-nine providers (167 PCPs, 82 cardiologists) participated in the study with a response rate of 18.8% (249/1320). Respondent mean years ±SD of experience since completing residency was 23.2 ± 13.8. Relative to cardiologists, less PCPs use CHADsVASC (36.8% vs. 74.4%) (p < 0.0001); more have never used HAS-BLED, HEMORR2HAGES, or ATRIA (38.5% vs. 9.8%) (p < .0001); more felt that their lack of knowledge/experience with DOACs was a barrier to prescribing the agents (p = 0.005); and more reported that they could use additional education on DOACs (87.0% vs. 47.0%) (p < 0.0001). Overall, cardiologists were more concerned about ischemic stroke outcomes, while PCPs were more concerned with GI bleeding. Cardiologists also felt that clinical trial data were most helpful in choosing the most appropriate DOAC for their patients, while PCPs felt that Real World Data was most useful. Conclusions: Cardiologists were more concerned with ischemic stroke while anticoagulating patients and utilized screening instruments like CHADsVASC in a majority of their patients. PCPs were concerned with GI bleeds when anticoagulating but nearly 40.0% utilized no screening tools to assess bleeding risk. Our findings show that future education about DOACs would be warranted especially with PCPs.
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spelling doaj.art-2930a43ddf654bccaf3b68c11718c7ac2022-12-21T17:59:17ZengSAGE PublishingClinical and Applied Thrombosis/Hemostasis1938-27232020-10-012610.1177/1076029620952550National Physician Survey for Nonvalvular Atrial Fibrillation (NVAF) Anticoagulation Comparing Knowledge, Attitudes and Practice of Cardiologist to PCPsHaseeb Saeed MD0Oscar Garza Ovalle MD1Ujala Bokhary MBBS2Anastasia Jermihov BS3Kamila Lepkowska MHA4Victoria Bauer BS5Kristine Kuchta MS6Marcia Wright PharmD7Scott Glosner BS, PharmD, BCPS, MPH8Margaret Frazer MD9Andres Quintero MD, MPH, MBA10Patrick Hlavacek MPH11Jack Mardekian PhD12Alfonso Tafur MD13Mark Metzl MD14Jorge Saucedo MD15 Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USA Pfizer Inc, New York, NY, USAIntroduction: NVAF is estimated to affect between 6.4 and 7.4 million Americans in 2018, and increases the risk of stroke 5-fold. To mitigate this risk, guidelines recommend anticoagulating AF patients unless their stroke risk is very low. Despite these recommendations, 30.0-60.0% of NVAF patients do not receive indicated anticoagulation. To better understand why this may be, we surveyed PCPs and cardiologists nationwide on their attitudes, knowledge and practices toward managing NVAF with warfarin and direct-acting oral anticoagulants (DOACs). Methods: We surveyed 1,000 PCPs and 500 cardiologists selected randomly from a master list of the American Medical Association, using a paper based, anonymous, self-administered, mailed scannable survey. The survey contained questions on key demographics and data concerning attitudes, knowledge and practices related to prescribing DOACs. The surveys went out in the fall/winter of 2017-8 with a $10 incentive gift card. Survey responses were scanned into an Excel database and analyzed using SAS 9.3 (Cary, NC) for descriptive and inferential statistics. Results: Two hundred and forty-nine providers (167 PCPs, 82 cardiologists) participated in the study with a response rate of 18.8% (249/1320). Respondent mean years ±SD of experience since completing residency was 23.2 ± 13.8. Relative to cardiologists, less PCPs use CHADsVASC (36.8% vs. 74.4%) (p < 0.0001); more have never used HAS-BLED, HEMORR2HAGES, or ATRIA (38.5% vs. 9.8%) (p < .0001); more felt that their lack of knowledge/experience with DOACs was a barrier to prescribing the agents (p = 0.005); and more reported that they could use additional education on DOACs (87.0% vs. 47.0%) (p < 0.0001). Overall, cardiologists were more concerned about ischemic stroke outcomes, while PCPs were more concerned with GI bleeding. Cardiologists also felt that clinical trial data were most helpful in choosing the most appropriate DOAC for their patients, while PCPs felt that Real World Data was most useful. Conclusions: Cardiologists were more concerned with ischemic stroke while anticoagulating patients and utilized screening instruments like CHADsVASC in a majority of their patients. PCPs were concerned with GI bleeds when anticoagulating but nearly 40.0% utilized no screening tools to assess bleeding risk. Our findings show that future education about DOACs would be warranted especially with PCPs.https://doi.org/10.1177/1076029620952550
spellingShingle Haseeb Saeed MD
Oscar Garza Ovalle MD
Ujala Bokhary MBBS
Anastasia Jermihov BS
Kamila Lepkowska MHA
Victoria Bauer BS
Kristine Kuchta MS
Marcia Wright PharmD
Scott Glosner BS, PharmD, BCPS, MPH
Margaret Frazer MD
Andres Quintero MD, MPH, MBA
Patrick Hlavacek MPH
Jack Mardekian PhD
Alfonso Tafur MD
Mark Metzl MD
Jorge Saucedo MD
National Physician Survey for Nonvalvular Atrial Fibrillation (NVAF) Anticoagulation Comparing Knowledge, Attitudes and Practice of Cardiologist to PCPs
Clinical and Applied Thrombosis/Hemostasis
title National Physician Survey for Nonvalvular Atrial Fibrillation (NVAF) Anticoagulation Comparing Knowledge, Attitudes and Practice of Cardiologist to PCPs
title_full National Physician Survey for Nonvalvular Atrial Fibrillation (NVAF) Anticoagulation Comparing Knowledge, Attitudes and Practice of Cardiologist to PCPs
title_fullStr National Physician Survey for Nonvalvular Atrial Fibrillation (NVAF) Anticoagulation Comparing Knowledge, Attitudes and Practice of Cardiologist to PCPs
title_full_unstemmed National Physician Survey for Nonvalvular Atrial Fibrillation (NVAF) Anticoagulation Comparing Knowledge, Attitudes and Practice of Cardiologist to PCPs
title_short National Physician Survey for Nonvalvular Atrial Fibrillation (NVAF) Anticoagulation Comparing Knowledge, Attitudes and Practice of Cardiologist to PCPs
title_sort national physician survey for nonvalvular atrial fibrillation nvaf anticoagulation comparing knowledge attitudes and practice of cardiologist to pcps
url https://doi.org/10.1177/1076029620952550
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