Associations between different tau-PET patterns and longitudinal atrophy in the Alzheimer’s disease continuum: biological and methodological perspectives from disease heterogeneity

Associations between different tau-PET patterns and longitudinal atrophy in the Alzheimer’s disease continuum: biological and methodological perspectives from disease heterogeneity

Abstract Background Subtypes and patterns are defined using tau-PET (tau pathology) and structural MRI (atrophy) in Alzheimer’s disease (AD). However, the relationship between tau pathology and atrophy across these subtypes/patterns remains unclear. Therefore, we investigated the biological associat...

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Bibliographic Details
Main Authors: Rosaleena Mohanty, Daniel Ferreira, Agneta Nordberg, Eric Westman, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease continuum
Heterogeneity
Tau-PET
Subtypes
Patterns
Longitudinal MRI
Online Access:https://doi.org/10.1186/s13195-023-01173-1

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