Psychogenic anorexia and non-alcoholic Wernicke's encephalopathy: Complete clinicoradiological recovery with thiamine
Rationale: Prolonged undernutrition may arise out of depression and lead to Wernicke's encephalopathy if timely diagnosis and intervention are missed. Wernicke's encephalopathy is potentially treatable, and appropriate treatment may revert clinical depression and cognitive dysfunction to s...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Acute Disease |
| Subjects: | |
| Online Access: | http://www.jadweb.org/article.asp?issn=2221-6189;year=2021;volume=10;issue=1;spage=42;epage=44;aulast=Ghosal |
| _version_ | 1818446050576302080 |
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| author | Anirban Ghosal Kajari Bhattacharya A Shobhana |
| author_facet | Anirban Ghosal Kajari Bhattacharya A Shobhana |
| author_sort | Anirban Ghosal |
| collection | DOAJ |
| description | Rationale: Prolonged undernutrition may arise out of depression and lead to Wernicke's encephalopathy if timely diagnosis and intervention are missed. Wernicke's encephalopathy is potentially treatable, and appropriate treatment may revert clinical depression and cognitive dysfunction to some extent.
Patient's concern: A 69-year-old female who had been taking escitalopram for one year developed tremor, ophthalmoplegia, ataxia, progressive cognitive decline, and convulsions.
Diagnosis: Non-alcoholic Wernicke's encephalopathy and hypomagnesemia due to psychogenic anorexia.
Interventions: High dose intravenous thiamine and magnesium were supplemented.
Outcomes: The patient showed remarkable improvement in neurological complications and even in depressive features.
Lessons: Wernicke's encephalopathy should not be ignored in the treatment of depression. |
| first_indexed | 2024-12-14T19:41:34Z |
| format | Article |
| id | doaj.art-293388ab73b74878954f8555f2ada04c |
| institution | Directory Open Access Journal |
| issn | 2221-6189 2589-5516 |
| language | English |
| last_indexed | 2024-12-14T19:41:34Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Acute Disease |
| spelling | doaj.art-293388ab73b74878954f8555f2ada04c2022-12-21T22:49:42ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892589-55162021-01-01101424410.4103/2221-6189.307394Psychogenic anorexia and non-alcoholic Wernicke's encephalopathy: Complete clinicoradiological recovery with thiamineAnirban GhosalKajari BhattacharyaA ShobhanaRationale: Prolonged undernutrition may arise out of depression and lead to Wernicke's encephalopathy if timely diagnosis and intervention are missed. Wernicke's encephalopathy is potentially treatable, and appropriate treatment may revert clinical depression and cognitive dysfunction to some extent. Patient's concern: A 69-year-old female who had been taking escitalopram for one year developed tremor, ophthalmoplegia, ataxia, progressive cognitive decline, and convulsions. Diagnosis: Non-alcoholic Wernicke's encephalopathy and hypomagnesemia due to psychogenic anorexia. Interventions: High dose intravenous thiamine and magnesium were supplemented. Outcomes: The patient showed remarkable improvement in neurological complications and even in depressive features. Lessons: Wernicke's encephalopathy should not be ignored in the treatment of depression.http://www.jadweb.org/article.asp?issn=2221-6189;year=2021;volume=10;issue=1;spage=42;epage=44;aulast=Ghosalwernicke's encephalopathy; non-alcoholic; treatment-resistant depression; thiamine |
| spellingShingle | Anirban Ghosal Kajari Bhattacharya A Shobhana Psychogenic anorexia and non-alcoholic Wernicke's encephalopathy: Complete clinicoradiological recovery with thiamine Journal of Acute Disease wernicke's encephalopathy; non-alcoholic; treatment-resistant depression; thiamine |
| title | Psychogenic anorexia and non-alcoholic Wernicke's encephalopathy: Complete clinicoradiological recovery with thiamine |
| title_full | Psychogenic anorexia and non-alcoholic Wernicke's encephalopathy: Complete clinicoradiological recovery with thiamine |
| title_fullStr | Psychogenic anorexia and non-alcoholic Wernicke's encephalopathy: Complete clinicoradiological recovery with thiamine |
| title_full_unstemmed | Psychogenic anorexia and non-alcoholic Wernicke's encephalopathy: Complete clinicoradiological recovery with thiamine |
| title_short | Psychogenic anorexia and non-alcoholic Wernicke's encephalopathy: Complete clinicoradiological recovery with thiamine |
| title_sort | psychogenic anorexia and non alcoholic wernicke s encephalopathy complete clinicoradiological recovery with thiamine |
| topic | wernicke's encephalopathy; non-alcoholic; treatment-resistant depression; thiamine |
| url | http://www.jadweb.org/article.asp?issn=2221-6189;year=2021;volume=10;issue=1;spage=42;epage=44;aulast=Ghosal |
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