Fever in a Patient with a Central Venous Catheter Colonized by Pandoraea pnomenusa
Pandoraea species are a newly described genus of multidrug-resistant, non-fermentative Gram-negative bacilli, mainly isolated from sputum samples of cystic fibrosis patients. In immunocompromised patients or with high antibiotic selective pressure, these pathogens are generally opportunistic and in...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Ordem dos Médicos
2022-05-01
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| Series: | Acta Médica Portuguesa |
| Subjects: | |
| Online Access: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16176 |
| _version_ | 1811242413074677760 |
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| author | Susana Ramos Oliveira Isabel Costa Monteiro Cristina Rodrigues Maria João Soares |
| author_facet | Susana Ramos Oliveira Isabel Costa Monteiro Cristina Rodrigues Maria João Soares |
| author_sort | Susana Ramos Oliveira |
| collection | DOAJ |
| description |
Pandoraea species are a newly described genus of multidrug-resistant, non-fermentative Gram-negative bacilli, mainly isolated from sputum samples of cystic fibrosis patients. In immunocompromised patients or with high antibiotic selective pressure, these pathogens are generally opportunistic and invasive. Although Pandoraea spp. are rare, the true incidence of these infections may be underestimated due to difficulties in microbial identification by phenotypic methods. We present the case of a 51-year-old woman, with new-onset fever after a prolonged hospitalization and multiple courses of antibiotics. Mass spectrometry assays identified Pandoraea pnomenusa in the blood cultures taken from the central venous catheter and in the catheter tip. Fever cessation after catheter removal suggests a catheter-related bloodstream infection. To the best of our knowledge, this is the first isolation of a Pandoraea spp. in Portugal, which should raise awareness to the emergence of these opportunistic and multidrug-resistant microorganisms, and the importance of its prompt identification.
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| first_indexed | 2024-04-12T13:50:57Z |
| format | Article |
| id | doaj.art-2935751b310a4d70878c36a5d1d49b8c |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-04-12T13:50:57Z |
| publishDate | 2022-05-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-2935751b310a4d70878c36a5d1d49b8c2022-12-22T03:30:32ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582022-05-01351310.20344/amp.16176Fever in a Patient with a Central Venous Catheter Colonized by Pandoraea pnomenusaSusana Ramos Oliveira0Isabel Costa Monteiro1Cristina Rodrigues2Maria João Soares3Serviço de Doenças Infecciosas. Hospital Pedro Hispano. Matosinhos. Unidade Local de Saúde de Matosinhos.Serviço de Medicina Interna. Hospital Pedro Hispano. Unidade Local de Saúde de Matosinhos. Matosinhos.Serviço de Medicina Interna. Hospital Pedro Hispano. Unidade Local de Saúde de Matosinhos. Matosinhos.Sector de Microbiologia. Serviço de Patologia Clínica. Hospital Pedro Hispano. Unidade Local de Saúde de Matosinhos. Matosinhos. Pandoraea species are a newly described genus of multidrug-resistant, non-fermentative Gram-negative bacilli, mainly isolated from sputum samples of cystic fibrosis patients. In immunocompromised patients or with high antibiotic selective pressure, these pathogens are generally opportunistic and invasive. Although Pandoraea spp. are rare, the true incidence of these infections may be underestimated due to difficulties in microbial identification by phenotypic methods. We present the case of a 51-year-old woman, with new-onset fever after a prolonged hospitalization and multiple courses of antibiotics. Mass spectrometry assays identified Pandoraea pnomenusa in the blood cultures taken from the central venous catheter and in the catheter tip. Fever cessation after catheter removal suggests a catheter-related bloodstream infection. To the best of our knowledge, this is the first isolation of a Pandoraea spp. in Portugal, which should raise awareness to the emergence of these opportunistic and multidrug-resistant microorganisms, and the importance of its prompt identification. https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16176Catheter-Related InfectionsCentral Venous Catheters/adverse effectsFeverPandoraea pnomenusa |
| spellingShingle | Susana Ramos Oliveira Isabel Costa Monteiro Cristina Rodrigues Maria João Soares Fever in a Patient with a Central Venous Catheter Colonized by Pandoraea pnomenusa Acta Médica Portuguesa Catheter-Related Infections Central Venous Catheters/adverse effects Fever Pandoraea pnomenusa |
| title | Fever in a Patient with a Central Venous Catheter Colonized by Pandoraea pnomenusa |
| title_full | Fever in a Patient with a Central Venous Catheter Colonized by Pandoraea pnomenusa |
| title_fullStr | Fever in a Patient with a Central Venous Catheter Colonized by Pandoraea pnomenusa |
| title_full_unstemmed | Fever in a Patient with a Central Venous Catheter Colonized by Pandoraea pnomenusa |
| title_short | Fever in a Patient with a Central Venous Catheter Colonized by Pandoraea pnomenusa |
| title_sort | fever in a patient with a central venous catheter colonized by pandoraea pnomenusa |
| topic | Catheter-Related Infections Central Venous Catheters/adverse effects Fever Pandoraea pnomenusa |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16176 |
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