VEGFR1-tyrosine kinase signaling in pulmonary fibrosis

VEGFR1-tyrosine kinase signaling in pulmonary fibrosis

Abstract Vascular endothelial growth factor (VEGF) is not only an important factor for angiogenesis but also lung development and homeostasis. VEGF-A binds three tyrosine kinase (TK) receptors VEGFR1–3. Idiopathic pulmonary fibrosis (IPF) is one of the poor prognoses of lung diseases. The relationsh...

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Bibliographic Details
Main Authors: Hideki Amano, Yoshio Matsui, Ko Hatanaka, Kanako Hosono, Yoshiya Ito
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Inflammation and Regeneration
Subjects:
Pulmonary fibrosis
VEGFR1-TK
VEGFR1+ cells
SDF-1
CXCR4
Online Access:https://doi.org/10.1186/s41232-021-00166-7

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