Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil
A lethal case of Brazilian spotted fever (BSF) is presented. Clinical features were initially of gastrointestinal involvement and evolved with progression to septic shock, meningoencephalitis and death on the 6th day of illness. Indirect immunofluorescence assay (IFA) for spotted fever group rickett...
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| Format: | Article |
| Language: | English |
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Elsevier
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| Series: | Brazilian Journal of Infectious Diseases |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000200010&lng=en&tlng=en |
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| author | Cristiane Lamas Alexsandra Favacho Tatiana Rozental Márcio N. Bóia Andrei H. Kirsten Alexandro Guterres Jairo Barreira Elba Regina S. de Lemos |
| author_facet | Cristiane Lamas Alexsandra Favacho Tatiana Rozental Márcio N. Bóia Andrei H. Kirsten Alexandro Guterres Jairo Barreira Elba Regina S. de Lemos |
| author_sort | Cristiane Lamas |
| collection | DOAJ |
| description | A lethal case of Brazilian spotted fever (BSF) is presented. Clinical features were initially of gastrointestinal involvement and evolved with progression to septic shock, meningoencephalitis and death on the 6th day of illness. Indirect immunofluorescence assay (IFA) for spotted fever group rickettsia (SFGR) was non-reactive. Diagnosis was confirmed by the polymerase chain reaction (PCR) and the nucleotide sequencing of a fragment of the ompA gene showed 100% homology to Rickettsia rickettsii. BSF has not been reported in the city of Rio de Janeiro in the last three decades, and the present description should alert the clinicians to its presence in urban Rio de Janeiro, and to the differential diagnosis with dengue fever, gastroenteritis, leptospirosis and bacterial septic shock, among others. |
| first_indexed | 2024-12-12T00:05:37Z |
| format | Article |
| id | doaj.art-293cde06f1f24fa8a9549c2b07f5f172 |
| institution | Directory Open Access Journal |
| issn | 1678-4391 |
| language | English |
| last_indexed | 2024-12-12T00:05:37Z |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj.art-293cde06f1f24fa8a9549c2b07f5f1722022-12-22T00:45:07ZengElsevierBrazilian Journal of Infectious Diseases1678-439112214915110.1590/S1413-86702008000200010S1413-86702008000200010Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, BrazilCristiane Lamas0Alexsandra Favacho1Tatiana Rozental2Márcio N. Bóia3Andrei H. Kirsten4Alexandro Guterres5Jairo Barreira6Elba Regina S. de Lemos7Laboratory of Hantaviruses and RickettsiosisLaboratory of Hantaviruses and RickettsiosisLaboratory of Hantaviruses and RickettsiosisFundação Oswaldo CruzLaboratory of Hantaviruses and RickettsiosisLaboratory of Hantaviruses and RickettsiosisLaboratory of Hantaviruses and RickettsiosisLaboratory of Hantaviruses and RickettsiosisA lethal case of Brazilian spotted fever (BSF) is presented. Clinical features were initially of gastrointestinal involvement and evolved with progression to septic shock, meningoencephalitis and death on the 6th day of illness. Indirect immunofluorescence assay (IFA) for spotted fever group rickettsia (SFGR) was non-reactive. Diagnosis was confirmed by the polymerase chain reaction (PCR) and the nucleotide sequencing of a fragment of the ompA gene showed 100% homology to Rickettsia rickettsii. BSF has not been reported in the city of Rio de Janeiro in the last three decades, and the present description should alert the clinicians to its presence in urban Rio de Janeiro, and to the differential diagnosis with dengue fever, gastroenteritis, leptospirosis and bacterial septic shock, among others.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000200010&lng=en&tlng=enBrazilian spotted feverspotted fever group rickettsiaRickettsia rickettsiilethal caseRio de Janeiro cityindirect immunofluorescencepolymerase chain reactioncentral nervous system involvement |
| spellingShingle | Cristiane Lamas Alexsandra Favacho Tatiana Rozental Márcio N. Bóia Andrei H. Kirsten Alexandro Guterres Jairo Barreira Elba Regina S. de Lemos Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil Brazilian Journal of Infectious Diseases Brazilian spotted fever spotted fever group rickettsia Rickettsia rickettsii lethal case Rio de Janeiro city indirect immunofluorescence polymerase chain reaction central nervous system involvement |
| title | Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil |
| title_full | Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil |
| title_fullStr | Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil |
| title_full_unstemmed | Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil |
| title_short | Characterization of rickettsia rickettsii in a case of Fatal Brazilian spotted fever in the city of Rio de Janeiro, Brazil |
| title_sort | characterization of rickettsia rickettsii in a case of fatal brazilian spotted fever in the city of rio de janeiro brazil |
| topic | Brazilian spotted fever spotted fever group rickettsia Rickettsia rickettsii lethal case Rio de Janeiro city indirect immunofluorescence polymerase chain reaction central nervous system involvement |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000200010&lng=en&tlng=en |
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