Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease

Local BMP2 hydrogel therapy for robust bone regeneration in a porcine model of Legg-Calvé-Perthes disease

Abstract Legg-Calvé-Perthes disease is juvenile idiopathic osteonecrosis of the femoral head (ONFH) that has no effective clinical treatment. Previously, local injection of bone morphogenetic protein-2 (BMP2) for ONFH treatment showed a heterogeneous bone repair and a high incidence of heterotopic o...

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Bibliographic Details
Main Authors: Chi Ma, Min Sung Park, Felipe Alves do Monte, Vishal Gokani, Olumide O. Aruwajoye, Yinshi Ren, Xiaohua Liu, Harry K. W. Kim
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-023-00322-2

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