Prenatal malnutrition and subsequent foetal loss risk: Evidence from the 1959-1961 Chinese famine

<b>Background</b>: Scientists disagree on whether prenatal malnutrition has long-term influences on women's reproductive function, and empirical evidence of such long-term effects remains limited and inconsistent. <b>Methods</b>: Using the retrospective pregnancy history...

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Main Author: Shige Song
Format: Article
Language:English
Published: Max Planck Institute for Demographic Research 2013-10-01
Series:Demographic Research
Subjects:
Online Access:http://www.demographic-research.org/volumes/vol29/26/
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author Shige Song
author_facet Shige Song
author_sort Shige Song
collection DOAJ
description <b>Background</b>: Scientists disagree on whether prenatal malnutrition has long-term influences on women's reproductive function, and empirical evidence of such long-term effects remains limited and inconsistent. <b>Methods</b>: Using the retrospective pregnancy history of 12,567 Chinese women collected in a nationally representative sample survey in 2001, this study conducted difference-in-differences analyses to investigate the relationship between prenatal exposure to the 1959-1961 Great Leap Forward Famine in China and the subsequent risk of involuntary foetal loss, including miscarriage and stillbirth, and how this relationship changes between the rural and urban populations. <b>Results</b>: Prenatal exposure to the Great Leap Forward Famine had no long-term effect on women's risk of miscarriage. Such an exposure increased the risk of stillbirth among urban women but not among rural women. <b>Conclusions</b>: The results support the foetal origins hypothesis. The significant urban-rural difference in the effect of prenatal famine exposure on stillbirth suggests the presence of a long-term negative foetal origins effect and a strong selection effect caused by famine-induced population attrition.
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spelling doaj.art-293f9e50cf9745ebb3148be6fdf9ef382022-12-21T20:08:33ZengMax Planck Institute for Demographic ResearchDemographic Research1435-98712013-10-012926Prenatal malnutrition and subsequent foetal loss risk: Evidence from the 1959-1961 Chinese famineShige Song<b>Background</b>: Scientists disagree on whether prenatal malnutrition has long-term influences on women's reproductive function, and empirical evidence of such long-term effects remains limited and inconsistent. <b>Methods</b>: Using the retrospective pregnancy history of 12,567 Chinese women collected in a nationally representative sample survey in 2001, this study conducted difference-in-differences analyses to investigate the relationship between prenatal exposure to the 1959-1961 Great Leap Forward Famine in China and the subsequent risk of involuntary foetal loss, including miscarriage and stillbirth, and how this relationship changes between the rural and urban populations. <b>Results</b>: Prenatal exposure to the Great Leap Forward Famine had no long-term effect on women's risk of miscarriage. Such an exposure increased the risk of stillbirth among urban women but not among rural women. <b>Conclusions</b>: The results support the foetal origins hypothesis. The significant urban-rural difference in the effect of prenatal famine exposure on stillbirth suggests the presence of a long-term negative foetal origins effect and a strong selection effect caused by famine-induced population attrition.http://www.demographic-research.org/volumes/vol29/26/difference-in-difference-in-differencefaminefoetal lossfoetal originsmultiple imputation
spellingShingle Shige Song
Prenatal malnutrition and subsequent foetal loss risk: Evidence from the 1959-1961 Chinese famine
Demographic Research
difference-in-difference-in-difference
famine
foetal loss
foetal origins
multiple imputation
title Prenatal malnutrition and subsequent foetal loss risk: Evidence from the 1959-1961 Chinese famine
title_full Prenatal malnutrition and subsequent foetal loss risk: Evidence from the 1959-1961 Chinese famine
title_fullStr Prenatal malnutrition and subsequent foetal loss risk: Evidence from the 1959-1961 Chinese famine
title_full_unstemmed Prenatal malnutrition and subsequent foetal loss risk: Evidence from the 1959-1961 Chinese famine
title_short Prenatal malnutrition and subsequent foetal loss risk: Evidence from the 1959-1961 Chinese famine
title_sort prenatal malnutrition and subsequent foetal loss risk evidence from the 1959 1961 chinese famine
topic difference-in-difference-in-difference
famine
foetal loss
foetal origins
multiple imputation
url http://www.demographic-research.org/volumes/vol29/26/
work_keys_str_mv AT shigesong prenatalmalnutritionandsubsequentfoetallossriskevidencefromthe19591961chinesefamine