Mechanistic insights into the role of amyloid-β in innate immunity

Abstract Colocalization of microbial pathogens and the β-amyloid peptide (Aβ) in the brain of Alzheimer’s disease (AD) patients suggests that microbial infection may play a role in sporadic AD. Aβ exhibits antimicrobial activity against numerous pathogens, supporting a potential role for Aβ in the i...

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Bibliographic Details
Main Authors: Tatum Prosswimmer, Anthony Heng, Valerie Daggett
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-55423-9