The Impact of Obesity on Diabetes Onset and Neovascularization in Mouse Models of Metabolic Stress

The Impact of Obesity on Diabetes Onset and Neovascularization in Mouse Models of Metabolic Stress

Animal models of metabolic disorders are essential to studying pathogenic mechanisms and developing therapies for diabetes, but the induction protocols vary, and sexual dimorphism often exists. In a chronic diabetic model of diet-induced obesity (DIO) and low-dose streptozotocin (STZ)-induced hyperg...

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Bibliographic Details
Main Authors: Sai Pranathi Meda Venkata, Hainan Li, Liping Xu, Jie-Mei Wang
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
hyperglycemia
dyslipidemia
animal model
neovascularization
sexual dimorphism
Online Access:https://www.mdpi.com/1422-0067/25/2/1214

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