Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity
Purpose: High fibular osteotomy (HFO) is a simple surgical technique to reduce pain and improve function in patients with osteoarthritis via fibular osteotomy. We report short-term results of HFO and mesenchymal cell induced chondrogenesis (MCIC) for the treatment of osteoarthritis of knee with varu...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-06-01
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| Series: | Regenerative Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352320418301093 |
| _version_ | 1819014647240458240 |
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| author | Hussain S.H. Jaheer Asode Ananthram Shetty Nam Yong Choi Ki-Won Kim Selvan V. Thirumal Jun Seob Song Ki Seong Kim You Seung Chun Seok Jung Kim |
| author_facet | Hussain S.H. Jaheer Asode Ananthram Shetty Nam Yong Choi Ki-Won Kim Selvan V. Thirumal Jun Seob Song Ki Seong Kim You Seung Chun Seok Jung Kim |
| author_sort | Hussain S.H. Jaheer |
| collection | DOAJ |
| description | Purpose: High fibular osteotomy (HFO) is a simple surgical technique to reduce pain and improve function in patients with osteoarthritis via fibular osteotomy. We report short-term results of HFO and mesenchymal cell induced chondrogenesis (MCIC) for the treatment of osteoarthritis of knee with varus deformity. Patients and methods: 45 symptomatic patients with 14 males and 31 females age ranging from 40 to 75 years were treated by HFO and MCIC. Main lesions involved medial compartment of knee and lateral compartment with normal to mild lesions of lateral meniscus and articular cartilage, amenable to treatment via partial meniscectomy or observation. Results: Knee injury and Osteoarthritis Outcome score and Lysholm showed a statistically significant increase and VAS, varus angle in X-ray showed a statistically significant decrease. A statistically significant difference between preoperative and postoperative scores was detected in male and female patients without any sexual differences. Conclusion: High fibular osteotomy and mesenchymal cell induced chondrogenesis can be considered as a good treatment option for medial compartment osteoarthritis of knee with varus deformity. Keywords: High fibular osteotomy, Osteoarthritis, Varus deformity, Knee, Mesenchymal cell induced chondrogenesis (MCIC) |
| first_indexed | 2024-12-21T02:19:10Z |
| format | Article |
| id | doaj.art-294b6e37cb054464ba12da47cfff1cc3 |
| institution | Directory Open Access Journal |
| issn | 2352-3204 |
| language | English |
| last_indexed | 2024-12-21T02:19:10Z |
| publishDate | 2019-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Regenerative Therapy |
| spelling | doaj.art-294b6e37cb054464ba12da47cfff1cc32022-12-21T19:19:12ZengElsevierRegenerative Therapy2352-32042019-06-0110112117Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformityHussain S.H. Jaheer0Asode Ananthram Shetty1Nam Yong Choi2Ki-Won Kim3Selvan V. Thirumal4Jun Seob Song5Ki Seong Kim6You Seung Chun7Seok Jung Kim8Department of Orthopaedic Surgery, Trauma & Orthopaedic Speciality Hospital (TOSH), Chennai, IndiaCanterbury Christ Church University, Faculty of Health and Social Sciences, 30 Pembroke Court, Chatham Maritime, Kent, ME4 4UF, United KingdomDepartment of Orthopaedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaDepartment of Orthopaedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaDepartment of Orthopaedic Surgery, Trauma & Orthopaedic Speciality Hospital (TOSH), Chennai, IndiaDepartment of Orthopaedic Surgery, JS Hospital, Seoul, South KoreaDepartment of Orthopaedic Surgery, Janghowon St. Mary's Hospital, Gyeonggi-do, South KoreaDepartment of Orthopaedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of KoreaDepartment of Orthopaedic Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea; Corresponding author. Dept. of Orthopedic Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 271, Cheonbo-ro, Uijeongbu-si, Gyeonggi-do, 11765, South Korea. Fax : +82.31 847 3671.Purpose: High fibular osteotomy (HFO) is a simple surgical technique to reduce pain and improve function in patients with osteoarthritis via fibular osteotomy. We report short-term results of HFO and mesenchymal cell induced chondrogenesis (MCIC) for the treatment of osteoarthritis of knee with varus deformity. Patients and methods: 45 symptomatic patients with 14 males and 31 females age ranging from 40 to 75 years were treated by HFO and MCIC. Main lesions involved medial compartment of knee and lateral compartment with normal to mild lesions of lateral meniscus and articular cartilage, amenable to treatment via partial meniscectomy or observation. Results: Knee injury and Osteoarthritis Outcome score and Lysholm showed a statistically significant increase and VAS, varus angle in X-ray showed a statistically significant decrease. A statistically significant difference between preoperative and postoperative scores was detected in male and female patients without any sexual differences. Conclusion: High fibular osteotomy and mesenchymal cell induced chondrogenesis can be considered as a good treatment option for medial compartment osteoarthritis of knee with varus deformity. Keywords: High fibular osteotomy, Osteoarthritis, Varus deformity, Knee, Mesenchymal cell induced chondrogenesis (MCIC)http://www.sciencedirect.com/science/article/pii/S2352320418301093 |
| spellingShingle | Hussain S.H. Jaheer Asode Ananthram Shetty Nam Yong Choi Ki-Won Kim Selvan V. Thirumal Jun Seob Song Ki Seong Kim You Seung Chun Seok Jung Kim Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity Regenerative Therapy |
| title | Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity |
| title_full | Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity |
| title_fullStr | Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity |
| title_full_unstemmed | Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity |
| title_short | Preliminary results of high fibular osteotomy (HFO) and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity |
| title_sort | preliminary results of high fibular osteotomy hfo and cartilage regeneration procedure for medial compartment osteoarthritis of knee with varus deformity |
| url | http://www.sciencedirect.com/science/article/pii/S2352320418301093 |
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