Anti-Cancer Properties of Theaflavins

Anti-Cancer Properties of Theaflavins

Cancer is a disease characterized by aberrant proliferative and apoptotic signaling pathways, leading to uncontrolled proliferation of cancer cells combined with enhanced survival and evasion of cell death. Current treatment strategies are sometimes ineffective in eradicating more aggressive, metast...

Full description

Bibliographic Details
Main Authors:	Eric J. O’Neill, Deborah Termini, Alexandria Albano, Evangelia Tsiani
Format:	Article
Language:	English
Published:	MDPI AG 2021-02-01
Series:	Molecules
Subjects:	cancer nutraceuticals theaflavins polyphenols apoptosis black tea
Online Access:	https://www.mdpi.com/1420-3049/26/4/987

Similar Items

Synthesis of Theaflavins and Their Functions
by: Masumi Takemoto, et al.
Published: (2018-04-01)

Theaflavins Improve Memory Impairment and Depression-Like Behavior by Regulating Microglial Activation
by: Yasuhisa Ano, et al.
Published: (2019-01-01)

Effects of Tea Polyphenols and Theaflavins on Three Oral Cariogenic Bacteria
by: Xia Cui, et al.
Published: (2023-08-01)

Potential anti-hyperglycemic activity of black tea theaflavins through inhibiting α-amylase
by: Maiquan Li, et al.
Published: (2024-06-01)

Theaflavins Are Improved by the Oxidation of Catechins in Tannase Treatment During Black Tea Fermentation
by: Lijuan Yang, et al.
Published: (2025-01-01)

Pear polyphenol oxidase enhances theaflavins in green tea soup through the enzymatic oxidation reaction
by: Yan Li, et al.
Published: (2022-10-01)

Milk Casein Inhibits Effect of Black Tea Galloylated Theaflavins to Inactivate SARS-CoV-2 In Vitro
by: Maiko Nakashio, et al.
Published: (2023-09-01)

Significant Inactivation of SARS-CoV-2 In Vitro by a Green Tea Catechin, a Catechin-Derivative, and Black Tea Galloylated Theaflavins
by: Eriko Ohgitani, et al.
Published: (2021-06-01)

Vasodilation of Tea Polyphenols Ex Vivo Is Mediated by Hydrogen Peroxide under Rapid Compound Decay
by: Mario Lorenz, et al.
Published: (2020-05-01)

An In Vitro Catalysis of Tea Polyphenols by Polyphenol Oxidase
by: Kunyi Liu, et al.
Published: (2023-02-01)

Degradation of black tea theaflavin through C-ring cleavage by gut microbiota
by: Shuwei Zhang, et al.
Published: (2022-05-01)

Research Progress on Anti-tumor Effects of Theaflavins
by: Xiaojing CHEN, et al.
Published: (2022-06-01)

Optimization of Enzymatic Oxidation Process and Quality Analysis of High-theaflavins Instant Black Tea
by: Jinxin LIU, et al.
Published: (2023-03-01)

Severe Acute Respiratory Syndrome Coronavirus-2 Inactivation Activity of the Polyphenol-Rich Tea Leaf Extract with Concentrated Theaflavins and Other Virucidal Catechins
by: Yohei Takeda, et al.
Published: (2021-08-01)

Research Progress on Anti-Tumor Mechanism of Theaflavins Natural Products
by: ZHANG Xue, et al.
Published: (2022-08-01)

Study on the Synthesis of Theaflavin-3,3′-Digallate Catalyzed by <em>Escherichia coli</em> Expressing Tea Tree Polyphenol Oxidase Isozymes and Its Enzymatic Solution
by: Changwei Liu, et al.
Published: (2023-08-01)

Rapid determination of theaflavins by HPLC with a new monolithic column
by: Jianyong Zhang, et al.
Published: (2019-04-01)

Theaflavin Induces Apoptosis of A375 Human Melanoma Cells and Inhibits Tumor Growth in Xenograft Zebrafishes Through P53- and JNK-Related Mechanism
by: Lei Zhang, et al.
Published: (2020-08-01)

Optimization of a tannase-assisted process for obtaining teas rich in theaflavins from Camelia sinensis leaves
by: Shuang Liang, et al.
Published: (2022-03-01)

Antidepressant, neuropharmacological activity and mode of action of theaflavin-3-gallate in in vitro and in vivo models of depression
by: Ying Wang, et al.
Published: (2018-11-01)

Determination of food additive theaflavins by ultraviolet spectrophotometry
by: ZHANG Haihong, et al.
Published: (2022-07-01)

Improvement of Theaflavins on Glucose and Lipid Metabolism in Diabetes Mellitus
by: Shiyu Xu, et al.
Published: (2024-06-01)

Improving Theaflavin-3,3′-digallate Production Efficiency Optimization by Transition State Conformation of Polyphenol Oxidase
by: Ying Huang, et al.
Published: (2023-04-01)

The hexane-ethyl acetate-methanol-water system for the separation of theaflavins from black tea (Camellia sinensis) using high-speed counter-current chromatography
by: N. Savitri Kumar, et al.
Published: (2016-09-01)

Protective Effects of Theaflavins and Epigallocatechin Gallate against ZnO-NP-Induced Cell Apoptosis In Vitro
by: Xiaodong Shan, et al.
Published: (2022-09-01)

Anti-hyperuricemic effects of three theaflavins isolated from black tea in hyperuricemic mice
by: Lingling Tai, et al.
Published: (2020-03-01)

Theaflavin-3,3′-digallate, a black tea polyphenol, stimulates lipolysis associated with the induction of mitochondrial uncoupling proteins and AMPK–FoxO3A–MnSOD pathway in 3T3-L1 adipocytes
by: Huey-Jiun Ko, et al.
Published: (2015-08-01)

The Effect of Theaflavins on the Gut Microbiome and Metabolites in Diabetic Mice
by: Jun Wang, et al.
Published: (2023-10-01)

Elucidation of structural difference in theaflavins for modulation of starch digestion
by: Ming Miao, et al.
Published: (2013-10-01)

Investigation of the Azorean <i>Camellia sinensis</i> Processing Conditions to Maximize the Theaflavin 3,3′-di-<i>O</i>-Gallate Content as a Potential Antiviral Compound
by: Lisete Paiva, et al.
Published: (2022-05-01)

Effect and Mechanism of Theaflavins on Fluoride Transport and Absorption in Caco-2 Cells
by: Yueqin Fan, et al.
Published: (2023-04-01)

Study on mechanism of low bioavailability of black tea theaflavins by using Caco-2 cell monolayer
by: Fengfeng Qu, et al.
Published: (2021-01-01)

Phytochemical Composition and Antioxidant Capacity of 30 Chinese Teas
by: Guo-Yi Tang, et al.
Published: (2019-06-01)

Study on the Interaction Mechanism of Theaflavin with Whey Protein: Multi-Spectroscopy Analysis and Molecular Docking
by: Jia Xu, et al.
Published: (2023-04-01)

Optimization of Fermentation Time for Iranian Black Tea Production
by: Masoud Hafezi, et al.
Published: (2006-03-01)

Simultaneous Determination of Epi-Catechins and Their Oxidized Dimers, Gallic Acid and Caffeine in Tea by HPLC
by: Kaixin ZHANG, et al.
Published: (2023-10-01)

Biotransformation of tea polyphenols by gut microbiota
by: Huadong Chen, et al.
Published: (2014-03-01)

Synergistic effect of black tea polyphenol, theaflavin-3,3′-digallate with cisplatin against cisplatin resistant human ovarian cancer cells
by: Haibo Pan, et al.
Published: (2018-07-01)

Antioxidant potential of theaflavin ameliorates the activities of key enzymes of glucose metabolism in high fat diet and streptozotocin – induced diabetic rats
by: Kirubananthan Gothandam, et al.
Published: (2019-01-01)

Antiobesity and lipid lowering effects of theaflavins on high-fat diet induced obese rats
by: Duiyan Jin, et al.
Published: (2013-07-01)