Saponins of sea cucumber attenuate atherosclerosis in ApoE−/− mice via lipid-lowering and anti-inflammatory properties

Saponins of sea cucumber attenuate atherosclerosis in ApoE−/− mice via lipid-lowering and anti-inflammatory properties

Atherosclerosis is an inflammatory disease linked to elevated blood cholesterol levels. Despite ongoing advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains the leading cause of death worldwide. The present study was conducted to evaluate the efficacy of the sa...

Full description

Bibliographic Details
Main Authors:	Lin Ding, Tian-Tian Zhang, Hong-Xia Che, Ling-Yu Zhang, Chang-Hu Xue, Yao-Guang Chang, Yu-Ming Wang
Format:	Article
Language:	English
Published:	Elsevier 2018-09-01
Series:	Journal of Functional Foods
Subjects:	Saponins Sea cucumber Atherosclerosis Lipid metabolism Inflammatory
Online Access:	http://www.sciencedirect.com/science/article/pii/S1756464618303815

Similar Items

Transcriptional Analysis of VEGF-D and TGFβ Genes in MCF7 Cells Exposed to Saponin Isolated from Holothuria leucospilota (Sea Cucumber)
by: Mozhgan Soltani, et al.
Published: (2015-10-01)

Evidence for a Saponin Biosynthesis Pathway in the Body Wall of the Commercially Significant Sea Cucumber Holothuria scabra
by: Shahida Akter Mitu, et al.
Published: (2017-11-01)

Absorption and Transport of Sea Cucumber Saponins from Apostichopus japonicus
by: Shuai Li, et al.
Published: (2016-06-01)

A Comparative Study of the Anti-Obesity Effects of Dietary Sea Cucumber Saponins and Energy Restriction in Response to Weight Loss and Weight Regain in Mice
by: Lu Wen, et al.
Published: (2022-10-01)

Saponins of North Atlantic Sea Cucumber: Chemistry, Health Benefits, and Future Prospectives
by: Oladapo F. Fagbohun, et al.
Published: (2023-04-01)

Putative mechanism for apoptosis-inducing properties of crude saponin isolated from sea cucumber (Holothuria leucospilota) as an antioxidant compound
by: Mozhgan Soltani, et al.
Published: (2015-02-01)

Antibacterial activity of Saponin extracted from the sea cucumber (Stichopus hermanni) collected from the Persian Gulf
by: Z. Salari; I. Sorinezhad; M. Nazemi; M. Yosefzadi
Published: (2018-01-01)

Molecular Networking-Based Analysis of Cytotoxic Saponins from Sea Cucumber <i>Holothuria atra</i>
by: Laura Grauso, et al.
Published: (2019-02-01)

Structural Elucidation of Novel Saponins in the Sea Cucumber Holothuria lessoni
by: Yadollah Bahrami, et al.
Published: (2014-08-01)

Characterization of a Coproduct from the Sea Cucumber <i>Cucumaria frondosa</i> and Its Effects on Visceral Adipocyte Size in Male Wistar Rats
by: Alan Ramalho, et al.
Published: (2020-10-01)

Synergistic effect of eicosapentaenoic acid-enriched phospholipids and sea cucumber saponin on orotic acid-induced non-alcoholic fatty liver disease in rats
by: Ying Guo, et al.
Published: (2018-01-01)

Advances in the Bioactivities of Phytochemical Saponins in the Prevention and Treatment of Atherosclerosis
by: Huiyu Luo, et al.
Published: (2022-11-01)

Discovery of Novel Saponins from the Viscera of the Sea Cucumber Holothuria lessoni
by: Yadollah Bahrami, et al.
Published: (2014-05-01)

In Vivo and Clinical Studies of Sea Cucumber-Derived Bioactives for Human Health and Nutrition From 2012-2021
by: Qi Liang, et al.
Published: (2022-07-01)

Absorption and pharmacokinetic study of two sulphated triterpenoid saponins in rat after oral and intravenous administration of saponin extracts of Pearsonothuria graeffei by HPLC-MS
by: Shanshan Song, et al.
Published: (2016-08-01)

Microwave-Assisted Desulfation of the Hemolytic Saponins Extracted from <i>Holothuria scabra</i> Viscera
by: Philippe Savarino, et al.
Published: (2022-01-01)

Difficulties and Countermeasures in Deep Processing of Sea Cucumber Viscera
by: Wenliang LIU, et al.
Published: (2023-10-01)

Structure Elucidation of New Acetylated Saponins, Lessoniosides A, B, C, D, and E, and Non-Acetylated Saponins, Lessoniosides F and G, from the Viscera of the Sea Cucumber Holothuria lessoni
by: Yadollah Bahrami, et al.
Published: (2015-01-01)

Distribution of Saponins in the Sea Cucumber <i>Holothuria lessoni</i>; the Body Wall Versus the Viscera, and Their Biological Activities
by: Yadollah Bahrami, et al.
Published: (2018-11-01)

Culturable Microorganisms Associated with Sea Cucumbers and Microbial Natural Products
by: Lei Chen, et al.
Published: (2021-08-01)

Features and Advantages of Supercritical CO<sub>2</sub> Extraction of Sea Cucumber <i>Cucumaria frondosa japonica</i> Semper, 1868
by: Alexander Zakharenko, et al.
Published: (2020-09-01)

Panax Notoginseng Saponins Promote Endothelial Progenitor Cell Mobilization and Attenuate Atherosclerotic Lesions in Apolipoprotein E Knockout Mice
by: Ya Liu, et al.
Published: (2013-09-01)

Enzymatic production of multifunctional bioactive peptides from sea cucumber (Actinopyga lecanora Jaeger)
by: Ghanbari, Raheleh
Published: (2014)

Biological and Pharmacological Effects of Synthetic Saponins
by: Yu-Pu Juang, et al.
Published: (2020-10-01)

Bioactive Compounds from Omani Sea Cucumbers
by: Sergey Dobretsov, et al.
Published: (2009-01-01)

Anticoagulant Properties of Protein Hydrolysates from the Muscle of Sea Cucumber
by: Samira Besharati, et al.
Published: (2017-02-01)

Profiles and Biological Values of Sea Cucumbers: A Mini Review
by: Siti Fathiah Masre
Published: (2018-12-01)

Cosmeceuticals Properties of Sea Cucumbers: Prospects and Trends
by: Evi Amelia Siahaan, et al.
Published: (2017-08-01)

Poecillastrosides, Steroidal Saponins from the Mediterranean Deep-Sea Sponge Poecillastra compressa (Bowerbank, 1866)
by: Kevin Calabro, et al.
Published: (2017-06-01)

Study on Composition and Antioxidant Properties of Sea Cucumber Peptides Prepared by Internal and External Enzymes
by: Chang LIU, et al.
Published: (2022-06-01)

Anti-viral effect of methanolic extract of Sea cucumber on HIV-1 virus
by: Bahroudi S, et al.
Published: (2015-12-01)

A Review on Heavy Metal Levels in Sea Cucumbers
by: Levent BAT, et al.
Published: (2020-12-01)

Sea Cucumber: New source of Protein for Human Consumption
by: Daniela Vaz Pratas
Published: (2014-06-01)

Antibacterial Activity of Sea Cucumbers Harvested from Karimunjawa
by: Delianis Pringgenies
Published: (2013-08-01)

Sea Cucumber Suppliers Selection Using Multi – Objective Optimization on The Basis of Ratio Analysis Methods
by: Cahyadi Indra, et al.
Published: (2022-01-01)

Artificial Reefs Reduce Morbidity and Mortality of Small Cultured Sea Cucumbers <i>Apostichopus japonicus</i> at High Temperature
by: Huiyan Wang, et al.
Published: (2023-04-01)

SEA CUCUMBER AS ANTICANCER AGENTS AND ITS DEVELOPMENT FOR FUNCTIONAL FOOD PRODUCTS
by: Sherly Ridhowati, et al.
Published: (2014-12-01)

Prevention Effect of Protopanaxadiol-Type Saponins Saponins and Protopanaxatriol-Type Saponins on Myelosuppression Mice Induced by Cyclophosphamide
by: He Zhang, et al.
Published: (2022-04-01)

20(<i>S</i>)-Protopanaxadiol Saponins Mainly Contribute to the Anti-Atherogenic Effects of <i>Panax notoginseng</i> in ApoE Deficient Mice
by: Conghui Liu, et al.
Published: (2019-10-01)

Constituents of sea cucumber Holothuria (mertensiothuria) leucospilota brandt with broad antibacterial activities
by: Ceesay, Abdoulie
Published: (2013)